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50-112-8629

CD169 (Siglec-1) Monoclonal Antibody (SER-4), PE, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-112-8629-Each-of-1 In Stock ₹ 35,079.60

50-112-8629 - Each of 1

₹ 35,079.60

In Stock

Quantity

1

Base Price: ₹ 35,079.60

GST (18%): ₹ 6,314.328

Total Price: ₹ 41,393.928

Antigen

CD169 (Siglec-1)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q62230

Gene Symbols

SIGLEC1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20612

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

SER-4

Conjugate

PE

Gene

SIGLEC1

Gene Alias

Cd169; dJ1009E24.1; macrophage receptor; p210; pSn; SA; SER; sheep erythrocyte receptor; sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC1; Siglec-1; SN

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Description

  • Description: The SER-4 monoclonal antibody reacts with mouse CD169, which is also known as Sialoadhesin and Siglec-1
  • CD169 is a 185-kDa member of the Siglec family of adhesion and endocytic receptors that recognize sialylated glycans
  • This receptor is expressed on a subset of macrophages that are found with high frequency in the spleen, liver, lymph node, and bone marrow
  • CD169 can also be detected on monocytes in the bone marrow and periphery
  • This receptor plays a role in cell-cell adhesion, as well as internalization of sialylated virus and bacteria
  • This endocytic pathway allows CD169+ macrophages to present lipid antigens to iNKT cells, thereby leading to their activation
  • Studies have also demonstrated that direct interaction of CD169 with regulatory T cells inhibits their proliferation
  • The SER-4 antibody has been reported to have antagonist activity
  • Applications Reported: This SER-4 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This SER-4 antibody has been tested by flow cytometric anaylsis of mouse bone marrow cells
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions
  • Family members include sialoadhesin, CD22 and CD33
  • Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.

Compare Similar Items

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Fischer Scientific

50-112-8629

--

Antigen:
CD169 (Siglec-1)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q62230
Gene Symbols:
SIGLEC1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20612
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
SER-4
Conjugate:
PE
Gene:
SIGLEC1
Gene Alias:
Cd169; dJ1009E24.1; macrophage receptor; p210; pSn; SA; SER; sheep erythrocyte receptor; sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1, sialoadhesin; Sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC1; Siglec-1; SN
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ

Img

Fischer Scientific

50-112-8630

--

Antigen:
EOMES
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O95936
Gene Symbols:
Eomes
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100622125, 8320
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
WD1928
Conjugate:
PE-Cyanine7
Gene:
Eomes
Gene Alias:
C77258; EOMES; eomesodermin; eomesodermin homolog; eomesodermin homolog (Xenopus laevis); T-box brain protein 2; T-box transcription factor; TBR2; TBR-2; T-brain-2
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Porcine
Product Type:
Antibody
Isotype:
IgG1 κ

Img

Fischer Scientific

50-112-8631

--

Antigen:
CD289 (TLR9)
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9NR96
Gene Symbols:
Tlr9
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54106
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
eB72-1665
Conjugate:
APC
Gene:
Tlr9
Gene Alias:
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a κ

Img

Invitrogen

50-112-8633

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Antigen:
Fc Receptor Binding Inhibitor
Classification:
__
Concentration:
5 μL/Test
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
__
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Fc blocking; FcR BI; FcR Inhibitor
Host Species:
Canine
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Canine
Product Type:
__
Isotype:
__