50-112-8639

TIGIT Monoclonal Antibody (GIGD7), eFluor™ 660, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-8639-Each-of-1 In Stock ₹ 34,052.88

50-112-8639 - Each of 1

₹ 34,052.88

In Stock

Quantity

1

Base Price: ₹ 34,052.88

GST (18%): ₹ 6,129.518

Total Price: ₹ 40,182.398

Antigen

TIGIT

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P86176

Gene Symbols

TIGIT

Immunogen

mTIGIT-Fc treated with 4% PFA

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

GIGD7

Conjugate

eFluor 660

Gene

TIGIT

Gene Alias

ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

Host Species

Rat

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100043314

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Related Products

Img

Invitrogen

25-575-282

--

Img

Invitrogen

25-575-742

--

Img

Invitrogen

17587082

--

Img

Invitrogen

17-108-382

--

Img

Invitrogen

14-365-882

--

Img

Invitrogen

50-112-4393

--

Img

Invitrogen

14318982

--

Img

Invitrogen

14-318-937

--

Description

  • Description: The GIGD7 monoclonal antibody reacts with mouse T cell immunoreceptor with Ig and ITIM domains (TIGIT, VSTM3, WUCAM), a 26 kDa protein that is a member of the poliovirus receptor (PVR) family
  • In mice, the expression of TIGIT has been reported in follicular T helper cells, while in humans, the expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells
  • TIGIT is not expressed on B cells or naive CD4+ T cells
  • TIGIT is upregulated on CD4+ T cells following activation
  • TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK cells and T cells with antigen presenting cells, fibroblasts and endothelial cells that express PVR and PVR-like proteins
  • Applications Reported: This GIGD7 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This GIGD7 antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 1 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • eFluor™ 660 is a replacement for Alexa Fluor™ 647
  • Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Compare Similar Items

Show Difference

Img

Invitrogen

50-112-8639

--


Antigen:
TIGIT

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P86176

Gene Symbols:
TIGIT

Immunogen:
mTIGIT-Fc treated with 4% PFA

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
GIGD7

Conjugate:
eFluor 660

Gene:
TIGIT

Gene Alias:
ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100043314

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-112-8640

--


Antigen:
CD304 (Neuropilin-1)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P97333

Gene Symbols:
NRP1

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
3DS304M

Conjugate:
eFluor 450

Gene:
NRP1

Gene Alias:
A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18186

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

50-112-8641

--


Antigen:
CD304 (Neuropilin-1)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P97333

Gene Symbols:
NRP1

Immunogen:
__

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
3DS304M

Conjugate:
APC

Gene:
NRP1

Gene Alias:
A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18186

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

50-112-8643

--


Antigen:
ROR gamma (t)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P51450

Gene Symbols:
Rorc

Immunogen:
__

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
B2D

Conjugate:
APC

Gene:
Rorc

Gene Alias:
EGK_01272; IMD42; MGC129539; NR1F3; nuclear receptor ROR-gamma; Nuclear receptor RZR-gamma; nuclear receptor subfamily 1 group F member 3; RAR related orphan receptor C; RAR-related orphan nuclear receptor variant 2; RAR-related orphan receptor C; RAR-related orphan receptor C, isoform a; RAR-related orphan receptor gamma; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; retinoid-related orphan receptor-gamma; ROR Gamma; ROR gamma t; Rorc; Rorg; RORgamma; RORgt; RP11-98D18.11-001; RZRG; RZR-GAMMA; Thor; Thymus orphan receptor; TOR

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19885

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid