50-112-8994

IL-25R (IL-17RB) Monoclonal Antibody (MUNC33), PE, eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-112-8994-Each-of-1 In Stock ₹ 14,374.08

50-112-8994 - Each of 1

₹ 14,374.08

In Stock

Quantity

1

Base Price: ₹ 14,374.08

GST (18%): ₹ 2,587.334

Total Price: ₹ 16,961.414

Antigen

IL-25R (IL-17RB)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q9JIP3

Gene Symbols

IL17RB

Immunogen

IL-17RB-Fc fusion protein

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

MUNC33

Conjugate

PE

Gene

IL17RB

Gene Alias

CRL4; cytokine receptor CRL4; cytokine receptor-like 4; ecotropic viral integration site 27; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL17BR; IL-17ER; Il17rb; IL-17RB; IL17RH1; IL-17Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7

Host Species

Rat

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

50905

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Description

  • Description: This MUNC33 monoclonal antibody reacts with mouse interleukin-25 receptor (IL-25R), also known as IL-17RB
  • IL-25R is a 55 kDa transmembrane protein that dimerizes with IL-17RA to form the functional receptor for IL-25 (IL-17E)
  • IL-25R is detectable in various tissues, including the lung and gastrointestinal tract and exists as both membrane bound and soluble form
  • IL-25/IL-25R interaction has been shown to activate the NF-kB, MAPK, and JNK pathways as well as gene transcription by STAT6, GATA-3, and NFATc1
  • IL-25R signals in T helper 2 (Th2) cells, type 2 innate lymphoid (ILC2) cells and some iNKT cells to promote differentiation and effector function
  • Whereas IL-25-deficient mice have an impaired Th2 response to parasitic helminth infection, elevated expression of IL-25 and IL-25R is observed in patients with chronic asthma and atopic dermatitis
  • Applications Reported: This MUNC33 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This MUNC33 antibody has been tested by flow cytometirc analysis of mouse lymph node cells or IL-25R-transfected cells
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified
  • These are termed as IL-17B, IL-17C (1) and IL-17E
  • IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth
  • IL-17B, C, and E like IL-17 are able to induce proinflammatory responses
  • However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist
  • Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively
  • IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8
  • IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.

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Fischer Scientific

50-112-8994

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Antigen:
IL-25R (IL-17RB)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q9JIP3

Gene Symbols:
IL17RB

Immunogen:
IL-17RB-Fc fusion protein

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
MUNC33

Conjugate:
PE

Gene:
IL17RB

Gene Alias:
CRL4; cytokine receptor CRL4; cytokine receptor-like 4; ecotropic viral integration site 27; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL17BR; IL-17ER; Il17rb; IL-17RB; IL17RH1; IL-17Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50905

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-112-8995

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Antigen:
BATF

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q16520

Gene Symbols:
Batf

Immunogen:
__

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
MBM7C7

Conjugate:
PerCP-eFluor 710

Gene:
Batf

Gene Alias:
activating transcription factor B; basic leucine zipper ATF-like transcription factor; basic leucine zipper transcription factor, ATF-like; basic leucine zipper transcription factor-like; basic leucine zipper transcriptional factor ATF-like; BATF; B-ATF; BATF1; B-cell activating transcription factor; B-cell-activating transcription factor; SFA2; SFA-2; SF-HT-activated gene 2 protein; si:ch211-153j24.4

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10538

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

50-112-8997

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Antigen:
CD31 (PECAM-1)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q08481

Gene Symbols:
Pecam1

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
390

Conjugate:
FITC

Gene:
Pecam1

Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18613

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Fischer Scientific

50-112-8998

--


Antigen:
CD86 (B7-2)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P42082

Gene Symbols:
CD86

Immunogen:
__

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
GL1

Conjugate:
eFluor 450

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rat

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12524

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid