50-112-9204

CD244.2 (2B4) Monoclonal Antibody (eBio244F4), APC, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-112-9204-Each-of-1 In Stock ₹ 27,122.52

50-112-9204 - Each of 1

₹ 27,122.52

In Stock

Quantity

1

Base Price: ₹ 27,122.52

GST (18%): ₹ 4,882.054

Total Price: ₹ 32,004.574

Antigen

CD244.2 (2B4)

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q07763

Gene Symbols

Cd244

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18106

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

eBio244F4

Conjugate

APC

Gene

Cd244

Gene Alias

2B4; C9.1; Cd244; CD244 long isoform; CD244 natural killer cell receptor 2B4; CD244 short isoform; F730046O15Rik; Ly90; NAIL; natural killer cell receptor; natural killer cell receptor 2B4; NK cell receptor 2B4; NK cell type I receptor protein 2B4; NKR2B4; Nmrk; non MHC restricted killing associated; non-MHC restricted killing associated; Signaling lymphocytic activation molecule 4; SLAM family member 4; SLAMF4

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a

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Description

  • Description: Mouse CD244, also known as 2B4, is a receptor belonging to the CD2 family of proteins involved in non-MHC dependent cytotoxicity
  • Expression is found on natural killer (NK) cells and many NKT cells and CD8+ cells
  • In C57BL/6 mice, two splice variants exist that differ in the length of the cytoplasmic domain
  • The long form functions in an inhibitory manner through signaling through SHP-2, while the short form functions in an activating manner
  • The ligand for CD244 is CD48 which is expressed on all hematopoietic cells
  • Recent data suggests that CD244 interactions with CD48, but not CD2 interaction with CD48, is essential for IL-2-driven expansion and activation of murine NK cells
  • Reports show CD244 expression can discriminate hematopoietic progenitors
  • Hematopoietic stem cells (HSC) are highly purified as CD150+CD244-CD48- cells while non-self-renewing multipotent hematopoietic progenitors (MPP) are CD244+CD150-CD48- and the most restricted progenitors are CD48+CD244+CD150-
  • eBio244F4 was generated against cell lines expressing CD244
  • It reacts with the C57BL/6 but not Balb/c due to polymorphisms present in the immunoglobulin V domain of the protein
  • The epitope recognized by eBio244F4 is different from that of 2B4; therefore these antibodies do not cross-block the binding to the respective epitopes
  • Applications Reported: This 244F4 antibody has been reported for use in flow cytometric analysis
  • This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing
  • The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity
  • Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Show Difference

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Invitrogen

50-112-9204

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Antigen:
CD244.2 (2B4)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q07763

Gene Symbols:
Cd244

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18106

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
eBio244F4

Conjugate:
APC

Gene:
Cd244

Gene Alias:
2B4; C9.1; Cd244; CD244 long isoform; CD244 natural killer cell receptor 2B4; CD244 short isoform; F730046O15Rik; Ly90; NAIL; natural killer cell receptor; natural killer cell receptor 2B4; NK cell receptor 2B4; NK cell type I receptor protein 2B4; NKR2B4; Nmrk; non MHC restricted killing associated; non-MHC restricted killing associated; Signaling lymphocytic activation molecule 4; SLAM family member 4; SLAMF4

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

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Fischer Scientific

50-112-9205

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Antigen:
CD335 (NKp46)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q8C567

Gene Symbols:
NCR1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17086

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
29A1.4

Conjugate:
PE-Cyanine7

Gene:
NCR1

Gene Alias:
1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

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Invitrogen

50-112-9206

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Antigen:
CD178 (Fas Ligand)

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P41047

Gene Symbols:
Fasl

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14103

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
MFL3

Conjugate:
PE-Cyanine7

Gene:
Fasl

Gene Alias:
ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form

Host Species:
Armenian Hamster

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Antigen:
CD38

Classification:
Monoclonal

Concentration:
5 μL/Test

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P28907

Gene Symbols:
CD38

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
952

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Flow Cytometry

Clone:
HIT2

Conjugate:
APC-eFluor 780

Gene:
CD38

Gene Alias:
2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADPRC 1; ADPRC1; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; Cd38; CD38 antigen; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase); CD38 antigen (p45); CD38 antigen p45; CD38 molecule; CD38H; Cd38-rs1; cluster of differentiation 38; cyclic ADP-ribose hydrolase 1; ecto-nicotinamide adenine dinucleotide glycohydrolase; I-19; NAD(+) nucleosidase; NAD+ nucleosidase; NIM-R5 antigen; T10

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ