50-113-7032

CD86 Monoclonal Antibody (GL1), PE-Cyanine7, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-113-7032-Each-of-1 In Stock ₹ 31,229.40

50-113-7032 - Each of 1

₹ 31,229.40

In Stock

Quantity

1

Base Price: ₹ 31,229.40

GST (18%): ₹ 5,621.292

Total Price: ₹ 36,850.692

Antigen

CD86, CD86 (B7-2)

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with proprietary stabilizer and <0.1% sodium azide

Gene Accession No.

P42082

Gene Symbols

CD86

Immunogen

Mouse CD86 from LPS-activated CBA/Ca mouse spleen B cells

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

Applications

Flow Cytometry

Clone

GL1

Conjugate

PE-Cyanine7

Gene

CD86

Gene Alias

activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species

Rat

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

12524

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • CD86 is one of two ligands (the other CD80) for CTLA4 and CD28
  • CD86 acts as costimulatory molecule in eliciting T-cell help during antigen presentation
  • Antigen presentation in the absence of sufficient co-stimulation involving CD86/CD80 can induce tolerance
  • CD80 appears to play a role distinct from CD80 in T helper cell differentiation
  • CD86 is a type I membrane protein that is a member of the immunoglobulin superfamily
  • The CD86 protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4
  • Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell
  • Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response
  • Alternative splicing results in two transcript variants encoding different isoforms of CD86
  • Additional transcript variants have been described for CD86, but their full-length sequences have not been determined
  • Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.

Compare Similar Items

Show Difference

Img

Invitrogen

50-113-7032

--


Antigen:
CD86, CD86 (B7-2)

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with proprietary stabilizer and <0.1% sodium azide

Gene Accession No.:
P42082

Gene Symbols:
CD86

Immunogen:
Mouse CD86 from LPS-activated CBA/Ca mouse spleen B cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry

Clone:
GL1

Conjugate:
PE-Cyanine7

Gene:
CD86

Gene Alias:
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2

Host Species:
Rat

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
12524

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-113-7033

--


Antigen:
Ly-49I

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
Klra9

Immunogen:
CHO-K1 cells transfected with the B6 allele of the Ly-49I gene, K1ra9

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
YLI-90

Conjugate:
FITC

Gene:
Klra9

Gene Alias:
5E6; Killer cell lectin-like receptor 3; killer cell lectin-like receptor subfamily A, member 9; Klra3; Klra9; Ly-49; Ly49C; Ly-49c; Ly49I; Ly49I receptor; Ly-49I receptor; LY49I1; Lymphocyte antigen 49c; Nk2.1; T-cell surface glycoprotein Ly-49C

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16640

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Invitrogen

50-113-7034

--


Antigen:
Ly-49I

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
0

Gene Symbols:
Klra9

Immunogen:
CHO-K1 cells transfected with the B6 allele of the Ly-49I gene, K1ra9

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry

Clone:
YLI-90

Conjugate:
PE

Gene:
Klra9

Gene Alias:
5E6; Killer cell lectin-like receptor 3; killer cell lectin-like receptor subfamily A, member 9; Klra3; Klra9; Ly-49; Ly49C; Ly-49c; Ly49I; Ly49I receptor; Ly-49I receptor; LY49I1; Lymphocyte antigen 49c; Nk2.1; T-cell surface glycoprotein Ly-49C

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16640

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Invitrogen

50-113-7037

--


Antigen:
CD103

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
Q60677

Gene Symbols:
Itgae

Immunogen:
Mouse CD103. from C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2

Applications:
Flow Cytometry

Clone:
2E7

Conjugate:
Pacific Blue

Gene:
Itgae

Gene Alias:
A530055J10; alpha-E1; alpha-M290; aM290; antigen CD103; antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide; CD103; DC; DCs; HML-1 antigen; human mucosal lymphocyte antigen 1, alpha polypeptide; HUMINAE; integrin alpha E; integrin alpha E, epithelial-associated; integrin alpha E1, epithelial-associated; integrin alpha M290; Integrin alpha-E; Integrin alpha-E heavy chain; Integrin alpha-E light chain; Integrin alpha-IEL; integrin subunit alpha E; integrin, alpha E; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); integrin, alpha E, epithelial-associated; Intregrin alpha E2; Itgae; MGC141996; Mucosal lymphocyte 1 antigen

Host Species:
Armenian Hamster

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
16407

Content And Storage:
4° C, store in dark

Form:
Liquid