50-113-7063
CD11a Monoclonal Antibody (MEM-25), APC, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-113-7063-Each-of-1 | In Stock | ₹ 20,619.96 |
50-113-7063 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,619.96
GST (18%): ₹ 3,711.593
Total Price: ₹ 24,331.553
Antigen
CD11a, itgal
Classification
Monoclonal
Conjugate
APC
Gene
ITGAL
Gene Alias
(p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species
Mouse
Purification Method
Size-exclusion chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3683
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
MEM-25
Formulation
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.
P20701
Gene Symbols
ITGAL
Immunogen
Leukocytes from a patient suffering from a LGL-type leukaemia
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin
- CD11a is implicated in activation of LFA-1 complex
- CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling
- CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation
- Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3
- CD11a is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions
- Blocking of CD11a function by specific antibodies or small molecules has become an important therapeutic approach in treatment of multiple inflammatory diseases
- For example, humanized anti- CD11a antibody Efalizumab (Raptiva) is being used to interfere with T cell migration to sites of inflammation, binding of cholesterol-lowering drug simvastatin to CD11a allosteric site leads to immunomodulation and increase in lymphocytic cholinergic activity
- Two transcript variants encoding different isoforms of CD11a have been found
- Diseases associated with CD11a dysfunction include benign cephalic histiocytosis and leukocyte adhesion deficiency.
Compare Similar Items
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Antigen: CD11a, itgal
Classification: Monoclonal
Conjugate: APC
Gene: ITGAL
Gene Alias: (p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3683
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: MEM-25
Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.: P20701
Gene Symbols: ITGAL
Immunogen: Leukocytes from a patient suffering from a LGL-type leukaemia
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CD11a, itgal
Classification:
Monoclonal
Conjugate:
APC
Gene:
ITGAL
Gene Alias:
(p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3683
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MEM-25
Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.:
P20701
Gene Symbols:
ITGAL
Immunogen:
Leukocytes from a patient suffering from a LGL-type leukaemia
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: CD59
Classification: Monoclonal
Conjugate: APC
Gene: CD59
Gene Alias: 16.3A5; 1F5; 1F5 antigen; 20 kDa homologous restriction factor; AA987121; Cb59b molecule; CD59; CD59 antigen; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 glycoprotein; CD59 molecule; CD59 molecule (CD59 blood group); CD59 molecule, complement regulatory protein; Cd59a; CD59a antigen; CD59A glycoprotein; Cd59b; CD59b antigen; CD59B glycoprotein; CD59b moleucle, complement regulatory protein; complement inhibitor CD59; complement regulatory protein; EJ16; EJ30; EL32; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MACIP; MAC-IP; MEM43; MEM43 antigen; membrane attack complex (MAC) inhibition factor; membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin; surface anitgen recognized by monoclonal antibody 16.3A5; T cell-activating protein
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 966
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: MEM-43
Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.: P13987
Gene Symbols: CD59
Immunogen: Thymocytes and T lymphocytes
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Antigen:
CD59
Classification:
Monoclonal
Conjugate:
APC
Gene:
CD59
Gene Alias:
16.3A5; 1F5; 1F5 antigen; 20 kDa homologous restriction factor; AA987121; Cb59b molecule; CD59; CD59 antigen; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 glycoprotein; CD59 molecule; CD59 molecule (CD59 blood group); CD59 molecule, complement regulatory protein; Cd59a; CD59a antigen; CD59A glycoprotein; Cd59b; CD59b antigen; CD59B glycoprotein; CD59b moleucle, complement regulatory protein; complement inhibitor CD59; complement regulatory protein; EJ16; EJ30; EL32; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MACIP; MAC-IP; MEM43; MEM43 antigen; membrane attack complex (MAC) inhibition factor; membrane attack complex inhibition factor; Membrane inhibitor of reactive lysis; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin; surface anitgen recognized by monoclonal antibody 16.3A5; T cell-activating protein
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
966
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MEM-43
Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.:
P13987
Gene Symbols:
CD59
Immunogen:
Thymocytes and T lymphocytes
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Antigen: HLA-G
Classification: Monoclonal
Conjugate: APC
Gene: HLA-G
Gene Alias: acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10
Host Species: Mouse
Purification Method: Size-exclusion chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3135
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: MEM-G/9
Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.: P17693
Gene Symbols: HLA-G
Immunogen: human HLA-G
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
HLA-G
Classification:
Monoclonal
Conjugate:
APC
Gene:
HLA-G
Gene Alias:
acrosomal protein SP-10; Acrosomal vesicle protein 1; ACRV1; b2 microglobulin; D11S4365; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; LOC768350; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; MHCIY; MHC-like class I Y; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G; SP-10; SPACA2; sperm protein 10
Host Species:
Mouse
Purification Method:
Size-exclusion chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3135
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MEM-G/9
Formulation:
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene Accession No.:
P17693
Gene Symbols:
HLA-G
Immunogen:
human HLA-G
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
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