50-113-8176
CD45R Monoclonal Antibody (RA3-6B2), Pacific Orange™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-113-8176-Each | In Stock | ₹ 39,584.33 |
50-113-8176 - Each
In Stock
Quantity
1
Base Price: ₹ 39,584.33
GST (18%): ₹ 7,125.179
Total Price: ₹ 46,709.509
Antigen
CD45R
Classification
Monoclonal
Conjugate
Pacific Orange
Gene
PTPRC
Gene Alias
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species
Rat
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
19264
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
RA3-6B2
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P06800
Gene Symbols
PTPRC
Immunogen
exon A-specific epitope on CD45
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- CD45R (PTPRC) is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- CD45 contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains
- CD45 is specifically expressed in hematopoietic cells and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling
- CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
- CD45 protein exists in multiple isoforms as a result of alternative splicing, and these isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains
- Further, these CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- In addition to its role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
- Diseases associated with CD45 dysfunction include Severe Combined Immunodeficiency (T-cell negative, B-Cell Negative) and Hepatitis C.
Compare Similar Items
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Antigen: CD45R
Classification: Monoclonal
Conjugate: Pacific Orange
Gene: PTPRC
Gene Alias: B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species: Rat
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 19264
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: RA3-6B2
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: P06800
Gene Symbols: PTPRC
Immunogen: exon A-specific epitope on CD45
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD45R
Classification:
Monoclonal
Conjugate:
Pacific Orange
Gene:
PTPRC
Gene Alias:
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species:
Rat
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
19264
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RA3-6B2
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
P06800
Gene Symbols:
PTPRC
Immunogen:
exon A-specific epitope on CD45
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD31
Classification: Monoclonal
Conjugate: Pacific Blue
Gene: Pecam1
Gene Alias: C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species: Rat
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18613
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: 390
Formulation: PBS with 0.1% sodium azide
Gene Accession No.: Q08481
Gene Symbols: Pecam1
Immunogen: Mouse 32D leukocyte cell line.
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD31
Classification:
Monoclonal
Conjugate:
Pacific Blue
Gene:
Pecam1
Gene Alias:
C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule
Host Species:
Rat
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18613
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
390
Formulation:
PBS with 0.1% sodium azide
Gene Accession No.:
Q08481
Gene Symbols:
Pecam1
Immunogen:
Mouse 32D leukocyte cell line.
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: CD19
Classification: Monoclonal
Conjugate: PE-Texas Red
Gene: Cd19
Gene Alias: AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
Host Species: Rat
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 12478
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: 6D5
Formulation: PBS with BSA, sucrose and 0.1% sodium azide
Gene Accession No.: P25918
Gene Symbols: Cd19
Immunogen: mouse CD19 antigen
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a
Antigen:
CD19
Classification:
Monoclonal
Conjugate:
PE-Texas Red
Gene:
Cd19
Gene Alias:
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12
Host Species:
Rat
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
12478
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
6D5
Formulation:
PBS with BSA, sucrose and 0.1% sodium azide
Gene Accession No.:
P25918
Gene Symbols:
Cd19
Immunogen:
mouse CD19 antigen
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a
Antigen: TNFR2, CD120B
Classification: Monoclonal
Conjugate: PE
Gene: Tnfrsf1b
Gene Alias: CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 7133
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: MR2-1
Formulation: PBS with 4mg/mL BSA, sucrose and 0.1% sodium azide
Gene Accession No.: P20333
Gene Symbols: Tnfrsf1b
Immunogen: Human CD120b (tumor necrosis factor receptor 75 kDa).
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
TNFR2, CD120B
Classification:
Monoclonal
Conjugate:
PE
Gene:
Tnfrsf1b
Gene Alias:
CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
7133
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
MR2-1
Formulation:
PBS with 4mg/mL BSA, sucrose and 0.1% sodium azide
Gene Accession No.:
P20333
Gene Symbols:
Tnfrsf1b
Immunogen:
Human CD120b (tumor necrosis factor receptor 75 kDa).
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1