50-122-36
CD266 (TWEAK Receptor) Monoclonal Antibody (ITEM-4), Biotin, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-122-36-Each-of-1 | In Stock | ₹ 29,518.20 |
50-122-36 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,518.20
GST (18%): ₹ 5,313.276
Total Price: ₹ 34,831.476
Antigen
CD266 (TWEAK Receptor)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
Q9CR75, Q9NP84
Gene Symbols
TNFRSF12A
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27279, 51330
Content And Storage
4° C, do not freeze
Form
Liquid
Applications
Flow Cytometry
Clone
ITEM-4
Conjugate
Biotin
Gene
TNFRSF12A
Gene Alias
AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- Description: The ITEM-4 antibody reacts with human TWEAK Receptor/Fn14 (fibroblast growth factor-inducible 14 kDa protein)
- Fn14 is distantly related to the TNFR family, containing one cysteine-rich domain in the extracellular region and a TNFR-associated factor binding domain but does not contain a death domain (DD) cytoplasmic region
- Fn14 plays a role in TWEAK-induced endothelial cell migration, proliferation, and angiogenesis
- TWEAK-induced cell death via Fn14 includes both apoptosis and necrosis and can be blocked by an anti-TWEAK antibody, CARL-1
- Fn14 is expressed on HUVEC and in some cancer tissues but not on freshly isolated PBMCs
- Fn14 mRNA expression has been identified during liver regeneration
- It has been reported that ITEM-4 cross-reacts with mouse Fn14
- In the mouse, Fn14 is reported to be constitutively expressed by Colon 26 cell line
- The ITEM-4 antibody has been show to have blocking function
- Applications Reported: The ITEM-4 antibody has been reported for use in flow cytometric analysis
- Applications Tested: The ITEM-4 antibody has been tested by flow cytometric analysis on human and mouse Fn14 transfected cells
- This can be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrate that this relatively small molecule is a fully transformed cell lines
- Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library
- TweakR is a small protein belonging to TNF receptor super family
- TweakR is capable of intiating a proliferative signal by binding to TRAF1, 2, and 3
- TweakR mRNA is upregulated during tissue regeneration in the aorta and liver
- It may also play a role in vascular cell migration and angiogenesis.
Compare Similar Items
Show Difference
Antigen: CD266 (TWEAK Receptor)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9CR75, Q9NP84
Gene Symbols: TNFRSF12A
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27279, 51330
Content And Storage: 4° C, do not freeze
Form: Liquid
Applications: Flow Cytometry
Clone: ITEM-4
Conjugate: Biotin
Gene: TNFRSF12A
Gene Alias: AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD266 (TWEAK Receptor)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9CR75, Q9NP84
Gene Symbols:
TNFRSF12A
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27279, 51330
Content And Storage:
4° C, do not freeze
Form:
Liquid
Applications:
Flow Cytometry
Clone:
ITEM-4
Conjugate:
Biotin
Gene:
TNFRSF12A
Gene Alias:
AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD282 (TLR2)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9QUN7
Gene Symbols: Tlr2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 24088
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen)
Clone: 6C2
Conjugate: Biotin
Gene: Tlr2
Gene Alias: CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a
Host Species: Rat
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2b κ
Antigen:
CD282 (TLR2)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9QUN7
Gene Symbols:
Tlr2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
24088
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Frozen)
Clone:
6C2
Conjugate:
Biotin
Gene:
Tlr2
Gene Alias:
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a
Host Species:
Rat
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2b κ
Antigen: CD283 (TLR3)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: O15455
Gene Symbols: TLR3
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7098
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TLR3.7
Conjugate: Biotin
Gene: TLR3
Gene Alias: AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1
Host Species: Mouse
Quantity: 25 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD283 (TLR3)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
O15455
Gene Symbols:
TLR3
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7098
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TLR3.7
Conjugate:
Biotin
Gene:
TLR3
Gene Alias:
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1
Host Species:
Mouse
Quantity:
25 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD289 (TLR9)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: Q9EQU3
Gene Symbols: Tlr9
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81897
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: M9.D6
Conjugate: Biotin
Gene: Tlr9
Gene Alias: CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species: Rat
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD289 (TLR9)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
Q9EQU3
Gene Symbols:
Tlr9
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81897
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
M9.D6
Conjugate:
Biotin
Gene:
Tlr9
Gene Alias:
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Host Species:
Rat
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG2a κ