50-128-93

CD144 (VE-cadherin) Monoclonal Antibody (eBioBV14 (BV14)), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-128-93-Each-of-1 In Stock ₹ 20,448.84

50-128-93 - Each of 1

₹ 20,448.84

In Stock

Quantity

1

Base Price: ₹ 20,448.84

GST (18%): ₹ 3,680.791

Total Price: ₹ 24,129.631

Antigen

CD144 (VE-cadherin)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P55284

Gene Symbols

CDH5

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12562

Content And Storage

4° C

Form

Liquid

Applications

Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone

eBioBV14 (BV14)

Conjugate

Unconjugated

Gene

CDH5

Gene Alias

7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b

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Description

  • Description: The BV14 monoclonal antibody reacts with mouse VE-Cadherin (CD144)
  • VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail
  • VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions
  • VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures
  • Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM)+ have the potential to give rise to hematopoietic cells
  • Cross-blocking experiments suggest that BV14 recognizes a different epitope than another mouse VE-Cadherin monoclonal antibody, BV13
  • Applications Reported: This eBioBV14 (BV14) antibody has been reported for use in immunoprecipitation, immunoblotting (WB), and immunohistology staining of frozen tissue sections
  • Intravenous injection of BV14 has been shown to induce a concentration- and time-dependent increase in vascular permeability in the heart and lungs, however BV13 was show to be more potent in this activity
  • (Please use Functional Grade purified eBioBV13 (BV13), cat
  • 16-1441, in functional assays.)
  • VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer
  • VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail
  • Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions
  • An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.

Compare Similar Items

Show Difference

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Fischer Scientific

50-128-93

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Antigen:
CD144 (VE-cadherin)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P55284

Gene Symbols:
CDH5

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12562

Content And Storage:
4° C

Form:
Liquid

Applications:
Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
eBioBV14 (BV14)

Conjugate:
Unconjugated

Gene:
CDH5

Gene Alias:
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Img

Fischer Scientific

50-128-94

--


Antigen:
CD144 (VE-cadherin)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P55284

Gene Symbols:
CDH5

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12562

Content And Storage:
4° C

Form:
Liquid

Applications:
Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
eBioBV14 (BV14)

Conjugate:
Unconjugated

Gene:
CDH5

Gene Alias:
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD

Host Species:
Rat

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b

Img

Invitrogen

50-128-96

--


Antigen:
CD144 (VE-cadherin)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P33151

Gene Symbols:
CDH5

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1003

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
16B1

Conjugate:
Unconjugated

Gene:
CDH5

Gene Alias:
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Invitrogen

50-128-98

--


Antigen:
CD146

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P43121, Q8R2Y2

Gene Symbols:
MCAM

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100342848, 4162, 489368, 84004

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
P1H12

Conjugate:
Unconjugated

Gene:
MCAM

Gene Alias:
1-gicerin; AV025631; CD146; CD149; Cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; l-gicerin; l-gicerin precursor; l-gicerin protein; LOW QUALITY PROTEIN: cell surface glycoprotein MUC18; MCAM; melanoma adhesion molecule; melanoma cell adhesion molecule; Melanoma-associated antigen A32; melanoma-associated antigen MUC18; Muc18; mucin-18; s-endo; S-endo 1 endothelial-associated antigen; s-gicerin; s-gicerin precursor

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Rabbit

Product Type:
Antibody

Isotype:
IgG1 κ