50-133-08

FceR1 alpha Monoclonal Antibody (MAR-1), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-133-08-Each-of-1 In Stock ₹ 28,405.92

50-133-08 - Each of 1

₹ 28,405.92

In Stock

Quantity

1

Base Price: ₹ 28,405.92

GST (18%): ₹ 5,113.066

Total Price: ₹ 33,518.986

Antigen

FceR1 alpha

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P20489

Gene Symbols

FCER1A

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14125

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

MAR-1

Conjugate

Unconjugated

Gene

FCER1A

Gene Alias

alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3

Host Species

Armenian Hamster

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description: The MAR-1 monoclonal antibody reacts with the Fc epsilon Receptor I alpha subunit, an IgE-binding subunit lacking signal-transducing ability
  • Fc epsilon RI alpha; is expressed on mast and basophil cells and is up-regulated by the presence of IgE
  • Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits
  • The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM)
  • The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions
  • Applications Reported: This MAR-1 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistology staining of frozen tissue sections
  • It has also been reported in degranulation of mast cells
  • (Please use Functional Grade purified MAR-1, cat
  • 16-5898, in functional assays.)
  • Applications Tested: The MAR-1 antibody has been tested by flow cytometric analysis of the MC/9 cell line (a mouse mast cell line)
  • This can be used at less than or equal to 0.25 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE
  • Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one β and two additional subunits
  • The latter two are required for signal transduction activity
  • The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response
  • When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released
  • The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma
  • The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-133-08

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Antigen:
FceR1 alpha

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P20489

Gene Symbols:
FCER1A

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14125

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
MAR-1

Conjugate:
Unconjugated

Gene:
FCER1A

Gene Alias:
alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3

Host Species:
Armenian Hamster

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-133-14

--


Antigen:
GL7

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
GL-7 (GL7)

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
GL7 antigen; Ly77; Ly-77

Host Species:
Rat

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgM

Img

Fischer Scientific

50-133-15

--


Antigen:
GL7

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
GL-7 (GL7)

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
GL7 antigen; Ly77; Ly-77

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgM

Img

Fischer Scientific

50-133-16

--


Antigen:
GL7

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
GL-7 (GL7)

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
GL7 antigen; Ly77; Ly-77

Host Species:
Rat

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgM