50-134-47

AIM2 Polyclonal Antibody, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 50-134-47-Each-of-1 In Stock ₹ 38,502.00

50-134-47 - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

AIM2

Classification

Polyclonal

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

O14862, Q91VJ1

Gene Symbols

AIM2

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

304987, 383619, 9447

Content And Storage

4° C

Form

Liquid

Applications

Western Blot

Conjugate

Unconjugated

Gene

AIM2

Gene Alias

Absent in melanoma 2; AIM2; Gm1313; Ifi210; ifi-210; Interferon-inducible protein 210; interferon-inducible protein AIM2; Interferon-inducible protein p210; PYHIN4; RP11-520H16.3

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Description: This polyclonal antibody reacts with human, mouse, and rat AIM2 (also known as Antigen isolated from Immunoselected Melanoma 2)
  • A member of the HIN-2000 family, this 40-kDa cytoplasmic protein is expressed in the spleen, small intestine, peripheral blood lymphocytes, and testis
  • Moreover, AIM2 is expressed in tumors of the neuroectodermis, breast, ovary, and colon
  • As a component of the inflammosome, AIM2 detects double-stranded viral and bacterial DNA present in the cytosol and initiates Caspase1 activation
  • Expression of AIM2 can be induced by interferons
  • Applications Reported: This polyclonal antibody has been reported for use in immunoblotting (WB)
  • Applications Tested: This polyclonal antibody has been tested by immunoblotting of Jurkat cells and mouse macrophages treated for 12 hrs with IFN gamma and LPS
  • This can be used at less than or equal to a 1:1000 dilution
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • AIM2 is a member of the IFI20X /IFI16 family
  • It plays a putative role in tumorigenic reversion and may control cell proliferation
  • Interferon-gamma induces expression of AIM2.

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50-134-47

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Antigen:
AIM2

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
O14862, Q91VJ1

Gene Symbols:
AIM2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
304987, 383619, 9447

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
AIM2

Gene Alias:
Absent in melanoma 2; AIM2; Gm1313; Ifi210; ifi-210; Interferon-inducible protein 210; interferon-inducible protein AIM2; Interferon-inducible protein p210; PYHIN4; RP11-520H16.3

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

50-134-4881

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Thermo Scientific

50-134-4925

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