50-135-85

Bax Monoclonal Antibody (1D1), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 50-135-85-Each-of-1 In Stock ₹ 23,101.20

50-135-85 - Each of 1

₹ 23,101.20

In Stock

Quantity

1

Base Price: ₹ 23,101.20

GST (18%): ₹ 4,158.216

Total Price: ₹ 27,259.416

Antigen

Bax

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q63690

Gene Symbols

BAX

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24887

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Clone

1D1

Conjugate

Unconjugated

Gene

BAX

Gene Alias

apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description: The 1D1 monoclonal antibody reacts with rat Bax (∽21 kDa), and does not react with human and mouse Bax
  • 1D1 shows no cross-reaction with Bcl-2 or Bcl-xL proteins
  • Bcl-2, Bax, and Bcl-xL are members of a protein family that regulates apoptosis; while several family members including Bcl-2 and Bcl-xL inhibit apoptosis, overexpression of Bax promotes programmed cell death
  • A rat Bax protein peptide sequence, aa 3-16, was used as immunogen
  • Applications Reported: The 1D1 antibody has been reported for use in immunoprecipitation, and immunoblotting (WB)
  • Applications Tested: The 1D1 antibody has been tested by Western Blot and can be used at approximately 1 μg/mL
  • 1D1 can also be used in IP at approximately 1-10 μg/mL
  • It is recommended that the reagent be carefully titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Aggregation: Less than 10%, as determined by HPLC
  • Filtration: 0.2 μm post-manufacturing filtered
  • BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis
  • Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function
  • Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2
  • The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain
  • Bcl-2 is also expressed in different Isoforms
  • Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha
  • Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa)
  • BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis
  • Overexpression of BAX functions to promote cell death
  • BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.

Compare Similar Items

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Invitrogen

50-135-85

--


Antigen:
Bax

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q63690

Gene Symbols:
BAX

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24887

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Clone:
1D1

Conjugate:
Unconjugated

Gene:
BAX

Gene Alias:
apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

50-135-88

--


Antigen:
IL-1 beta

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P10749, Q63264

Gene Symbols:
IL1B

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16176, 24494

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Functional Assay, Neutralization

Clone:
B122

Conjugate:
Unconjugated

Gene:
IL1B

Gene Alias:
catabolin; cytokine; Hematopoietin 1 (H1); IFN beta inducing factor; il 1b; IL 1β; IL-1; IL1 B; IL-1 beta; IL-1 precursor; IL1B; IL-1B; IL1B1; IL1beta; IL-1beta; IL1-BETA; IL1F2; IL1β; ILN; Interleukin; interleukin 1 beta; Interleukin 1 beta precursor; interleukin 1, beta; interleukin 1, beta 1; interleukin 1-beta; interleukin*1*beta; Interleukin1 beta; interleukin-1 beta; interleukin-1 beta precursor; interleukin-1 beta precursor (AA -113 to 153); interleukin-1 beta proprotein; interleukin-1b; interleukin-1beta; interleukin-beta; LAF; lymphocyte proliferation-potentiating factor; Osteoclast activating factor (OAF); preinterleukin 1 beta; Pro interleukin 1 beta; prointerleukin-1 beta; pro-interleukin-1-beta

Host Species:
Armenian Hamster

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-135-89

--


Antigen:
IL-1 beta

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P10749, Q63264

Gene Symbols:
IL1B

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16176, 24494

Content And Storage:
4° C

Form:
Liquid

Applications:
ELISA, Functional Assay, Neutralization

Clone:
B122

Conjugate:
Unconjugated

Gene:
IL1B

Gene Alias:
catabolin; cytokine; Hematopoietin 1 (H1); IFN beta inducing factor; il 1b; IL 1β; IL-1; IL1 B; IL-1 beta; IL-1 precursor; IL1B; IL-1B; IL1B1; IL1beta; IL-1beta; IL1-BETA; IL1F2; IL1β; ILN; Interleukin; interleukin 1 beta; Interleukin 1 beta precursor; interleukin 1, beta; interleukin 1, beta 1; interleukin 1-beta; interleukin*1*beta; Interleukin1 beta; interleukin-1 beta; interleukin-1 beta precursor; interleukin-1 beta precursor (AA -113 to 153); interleukin-1 beta proprotein; interleukin-1b; interleukin-1beta; interleukin-beta; LAF; lymphocyte proliferation-potentiating factor; Osteoclast activating factor (OAF); preinterleukin 1 beta; Pro interleukin 1 beta; prointerleukin-1 beta; pro-interleukin-1-beta

Host Species:
Armenian Hamster

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-135-98

--


Antigen:
IL-2

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
P04351

Gene Symbols:
IL2

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16183

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Immunostaining

Clone:
JES6-1A12

Conjugate:
Unconjugated

Gene:
IL2

Gene Alias:
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF

Host Species:
Rat

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ