50-138-34

Musashi-1 Monoclonal Antibody (14H1), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-138-34-Each-of-1 In Stock ₹ 15,315.24

50-138-34 - Each of 1

₹ 15,315.24

In Stock

Quantity

1

Base Price: ₹ 15,315.24

GST (18%): ₹ 2,756.743

Total Price: ₹ 18,071.983

Antigen

Musashi-1

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

O43347, Q61474, Q8K3P4

Gene Symbols

MSI1

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17690, 259272, 4440

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

14H1

Conjugate

Unconjugated

Gene

MSI1

Gene Alias

fb40b12; hypothetical protein LOC541389; m-Msi-1; ms1; msi1; msi1b; Msi1h; Musahi1; musashi homolog 1; Musashi homolog 1(Drosophila); musashi RNA binding protein 1; musashi RNA binding protein 1b; musashi RNA-binding protein 1; musashi1; musashi-1; RNA-binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1 L+35bp; RNA-binding protein Musashi homolog 1 Long; RNA-binding protein Musashi homolog 1b; wu:fb40b12; zgc:103751; zMsi1

Host Species

Rat

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG2a

Description

  • Description: This 14H1 monoclonal antibody recognizes human Musashi-1 (MSI-1), a 39 kDa RNA binding protein
  • Musashi-1 is expressed in CNS stem and progenitor cells with decreased expression in differentiating cells
  • Musashi-1 functions as a translational repressor, directly regulating its target proteins, Numb and p21 (CIP1)
  • Musashi-1 has been shown to be expressed in stem cells in a variety of other tissues such as the gut, stomach, mammary gland, and hair follicles
  • In addition to normal tissue expression, Musashi-1 expression has been identified in cells from several tumor types, mainly pulmonary and adenocarcinoma, as well as large and small cell carcinomas
  • Recently, expression of Musashi-1 in ischemic lesions following stroke provides evidence for neurogenesis as well as the role of Musashi-1 in regulating apoptosis
  • Musashi-1 is highly conserved and the 14H1 antibody also recognizes mouse and rat Musashi-1
  • Applications Reported: This 14H1 antibody has been reported for use in immunoblotting (WB), immunohistology staining of paraffin embedded tissue sections, and immunocytochemistry
  • Applications Tested: This 14H1 antibody has been tested by immunofluorescent staining of paraformaldehyde fixed and permeabilized cells
  • This can be used at less than or equal to 10 μg/mL
  • It is recommended that the antibody be titrated for optimal performance in the assay of interest
  • Purity: Greater than 90%, as determined by SDS-PAGE
  • Musashi-1 belongs to the Musashi family of RNA-binding proteins which play a role in cell fate determination, and maintenance of stem-cell state
  • Musashi family proteins are also involved in post transcriptional gene regulation
  • The gene encodes a protein with two conserved tandem RNA recognition motifs with highly conserved RNP (ribonucleoprotein) motifs
  • In mammals, Musashi-1 is expressed in fetal kidney, brain, liver and lung, and in adult brain and pancreas
  • In humans, the gene is located on chromosome 12.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-138-34

--


Antigen:
Musashi-1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
O43347, Q61474, Q8K3P4

Gene Symbols:
MSI1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17690, 259272, 4440

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
14H1

Conjugate:
Unconjugated

Gene:
MSI1

Gene Alias:
fb40b12; hypothetical protein LOC541389; m-Msi-1; ms1; msi1; msi1b; Msi1h; Musahi1; musashi homolog 1; Musashi homolog 1(Drosophila); musashi RNA binding protein 1; musashi RNA binding protein 1b; musashi RNA-binding protein 1; musashi1; musashi-1; RNA-binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1 L+35bp; RNA-binding protein Musashi homolog 1 Long; RNA-binding protein Musashi homolog 1b; wu:fb40b12; zgc:103751; zMsi1

Host Species:
Rat

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Img

Fischer Scientific

50-138-35

--


Antigen:
Musashi-1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
O43347, Q61474, Q8K3P4

Gene Symbols:
MSI1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17690, 259272, 4440

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
14H1

Conjugate:
Unconjugated

Gene:
MSI1

Gene Alias:
fb40b12; hypothetical protein LOC541389; m-Msi-1; ms1; msi1; msi1b; Msi1h; Musahi1; musashi homolog 1; Musashi homolog 1(Drosophila); musashi RNA binding protein 1; musashi RNA binding protein 1b; musashi RNA-binding protein 1; musashi1; musashi-1; RNA-binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1 L+35bp; RNA-binding protein Musashi homolog 1 Long; RNA-binding protein Musashi homolog 1b; wu:fb40b12; zgc:103751; zMsi1

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

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Hampton Research

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