50-139-76
Perforin Monoclonal Antibody (eBioBOR21), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 50-139-76-Each | In Stock | ₹ 27,434.81 |
50-139-76 - Each
In Stock
Quantity
1
Base Price: ₹ 27,434.81
GST (18%): ₹ 4,938.266
Total Price: ₹ 32,373.076
Antigen
Perforin
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P14222
Gene Symbols
PRF1
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5551
Content And Storage
4° C
Form
Liquid
Applications
Western Blot
Clone
eBioBOR21
Conjugate
Unconjugated
Gene
PRF1
Gene Alias
Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b
Description
- Description: The eBioBOR21 antibody clone reacts with human perforin (pore-forming protein, pfp)
- Perforin is one of the cytolytic mediators present in the cytoplasmic granules of cytotoxic T lymphocytes (CTL) and natural killer cells (NK)
- Perforin is involved in the killing function by CTLs and NKs and has an important role in the immune response against tumors and virus infections
- Applications Tested: The eBioBOR21 antibody has been tested for use in immunoblotting (WB) of human PBMCs at 1-5 μg/mL
- It is recommended that this antibody be titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- Perforin is one of the major cytolytic proteins of cytolytic granules
- Perforin is a cytolytic mediator and is stored in and released by cytoplasmic granules
- Moreover, perforin is involved in immune defense against tumors and virus infections as mediated by cytotoxic lymphocytes
- Perforin is a 555 amino acid protein with a 21 amino acid signal peptide, and has a molecular weight of 70 to 75 kD
- Perforin is a pore forming protein with a mechanism of transmembrane channel formation similar to C9, and homology between perforin and C9 have been demonstrated
- Studies show that perforin is expressed only in killer cell lines and not in helper T lymphocytes or other tumor cells tested
- Perforin is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
- Defects in the perforin gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood
- Alternative splicing results in multiple transcript variants of perforin.
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Antigen: Perforin
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P14222
Gene Symbols: PRF1
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5551
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Clone: eBioBOR21
Conjugate: Unconjugated
Gene: PRF1
Gene Alias: Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Antigen:
Perforin
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P14222
Gene Symbols:
PRF1
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5551
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Clone:
eBioBOR21
Conjugate:
Unconjugated
Gene:
PRF1
Gene Alias:
Cyta; Cytolysin; FLH2; HPLH2; lymphocyte pore forming protein; lymphocyte pore-forming protein; OMAK; OTTHUMP00000019759; P1; perforin 1; perforin 1 (pore forming protein); Perforin1; perforin-1; Pfn; PFN1; Pfp; PGFL; PIGF; PIGF-2; PLGF; pore forming protein; pore-forming protein; PRF1; Prf-1; PRF1 (pore forming protein 1); RATCYTA; RP11-710A11.3
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Gene Symbols: __
Purification Method: __
Regulatory Status: __
Gene ID (Entrez): __
Content And Storage: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Gene Alias: __
Host Species: __
Quantity: __
Primary or Secondary: __
Target Species: __
Product Type: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Gene Symbols:
__
Purification Method:
__
Regulatory Status:
__
Gene ID (Entrez):
__
Content And Storage:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Gene Alias:
__
Host Species:
__
Quantity:
__
Primary or Secondary:
__
Target Species:
__
Product Type:
__
Isotype:
__
Antigen: IgM
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P01871
Gene Symbols: IGHM
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3507
Content And Storage: 4° C
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen)
Clone: SA-DA4
Conjugate: Unconjugated
Gene: IGHM
Gene Alias: AGM1; IGHM; immunoglobulin heavy constant mu; MU; VH
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
IgM
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P01871
Gene Symbols:
IGHM
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3507
Content And Storage:
4° C
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen)
Clone:
SA-DA4
Conjugate:
Unconjugated
Gene:
IGHM
Gene Alias:
AGM1; IGHM; immunoglobulin heavy constant mu; MU; VH
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD2
Classification: Monoclonal
Concentration: 5 μL/Test
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.: P06729, Q6SZ61
Gene Symbols: CD2
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100126712, 102120798, 396662, 449512, 677855, 914
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: RPA-2.10
Conjugate: PE-Cyanine5
Gene: CD2
Gene Alias: Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
Host Species: Mouse
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Porcine, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
CD2
Classification:
Monoclonal
Concentration:
5 μL/Test
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P06729, Q6SZ61
Gene Symbols:
CD2
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100126712, 102120798, 396662, 449512, 677855, 914
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
RPA-2.10
Conjugate:
PE-Cyanine5
Gene:
CD2
Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
Host Species:
Mouse
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Baboon, Chimpanzee, Cynomolgus Monkey, Human, Non-human Primate, Porcine, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1 κ