50-142-51

CD19 Monoclonal Antibody (eBio1D3 (1D3)), Functional Grade, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

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Pack Size SKU Availability Price
Each of 1 50-142-51-Each-of-1 In Stock ₹ 32,683.92

50-142-51 - Each of 1

₹ 32,683.92

In Stock

Quantity

1

Base Price: ₹ 32,683.92

GST (18%): ₹ 5,883.106

Total Price: ₹ 38,567.026

Antigen

CD19

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative; pH 7.2

Gene Accession No.

P25918

Gene Symbols

Cd19

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12478

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)

Clone

eBio1D3 (1D3)

Conjugate

Functional Grade

Gene

Cd19

Gene Alias

AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

Host Species

Rat

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Description: The eBio1D3 monoclonal antibody reacts with mouse CD19, a 95 kDa transmembrane glycoprotein
  • CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells
  • Follicular dendritic cells also express CD19
  • Together CD21, CD81, MHC class II, and CD19 form a multimolecular complex that associates with the BCR
  • Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells
  • Applications Reported: This eBio1D3 (1D3) antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections
  • The eBio1D3 monoclonal antibody has also been reported to induce down-regulation of CD19, affecting the proportions of B-1a and B-2 B cells in mice
  • Applications Tested: This eBio1D3 (1D3) antibody has been tested by flow cytometric analysis of mouse splenocytes
  • This can be used at less than or equal to 0.5 μg per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
  • Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay
  • Storage and handling: Use in a sterile environment
  • Filtration: 0.2 μm post-manufacturing filtered
  • CD19 is a member of the immunoglobulin superfamily and has two Ig like domains
  • The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains
  • CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage
  • Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen
  • The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation, and is expressed in all B cell precursor leukemias
  • Lymphocytes proliferate and differentiate in response to various concentrations of different antigens
  • The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors
  • CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation
  • Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge
  • Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.

Compare Similar Items

Show Difference

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Invitrogen

50-142-51

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Antigen:
CD19

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P25918

Gene Symbols:
Cd19

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12478

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)

Clone:
eBio1D3 (1D3)

Conjugate:
Functional Grade

Gene:
Cd19

Gene Alias:
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

Host Species:
Rat

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Img

Invitrogen

50-142-52

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Antigen:
CD19

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P15391

Gene Symbols:
Cd19

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
930

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay

Clone:
HIB19

Conjugate:
Functional Grade

Gene:
Cd19

Gene Alias:
AW495831; B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Cd19; CD19 antigen; CD19 molecule; CVID3; differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

Host Species:
Mouse

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Img

Fischer Scientific

50-142-53

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Antigen:
CD20

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P19437

Gene Symbols:
Ms4a1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12482

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Western Blot

Clone:
AISB12

Conjugate:
Functional Grade

Gene:
Ms4a1

Gene Alias:
AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a

Img

Fischer Scientific

50-142-54

--


Antigen:
CD20

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
P19437

Gene Symbols:
Ms4a1

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12482

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Western Blot

Clone:
AISB12

Conjugate:
Functional Grade

Gene:
Ms4a1

Gene Alias:
AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7

Host Species:
Rat

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a