50-155-6779
DNMT1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-6779-Each-of-1 | In Stock | ₹ 41,863.65 |
50-155-6779 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
DNMT1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DNMT1
Gene Alias
Dnmt1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1786
Content And Storage
4° C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
P26358
Gene Symbols
DNMT1
Immunogen
Between 350 and 400
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development
- Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer
- To date, 3 families of mammalian DNA methyltransferase genes have been identified which include Dnmt1, Dnmt2 and Dnmt3
- Dnmt1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality
- Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintece of methylation
- The Dnmt3 family members, Dnmt3a and Dnmt3b, are strongly expressed in ES cells but their expression is down regulated in differentiating ES cells and is low in adult somatic tissue
- Dnmt1 co-purifies with the retinoblastoma (Rb) tumour suppressor gene product, E2F1, and HDAC1
- Dnmt1 also cooperates with Rb to repress transcription from promoters containing E2F-binding sites suggesting a link between DNA methylation, histone deacetylase and sequence-specific DNA binding activity, as well as a growth-regulatory pathway that is disrupted in nearly all cancer cells.
Compare Similar Items
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Antigen: DNMT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNMT1
Gene Alias: Dnmt1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1786
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: P26358
Gene Symbols: DNMT1
Immunogen: Between 350 and 400
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DNMT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNMT1
Gene Alias:
Dnmt1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1786
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P26358
Gene Symbols:
DNMT1
Immunogen:
Between 350 and 400
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DNMT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNMT1
Gene Alias: Dnmt1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1786
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: P26358
Gene Symbols: DNMT1
Immunogen: Between 350 and 400
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DNMT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNMT1
Gene Alias:
Dnmt1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1786
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
P26358
Gene Symbols:
DNMT1
Immunogen:
Between 350 and 400
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CSN7b
Classification: Polyclonal
Conjugate: Unconjugated
Gene: COPS7B
Gene Alias: COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 7B, COP9 constitutive photomorphogenic homolog subunit 7B, COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis), CSN7B, JAB1-containing signalosome subunit 7b, SGN7b, signalosome subunit 7b
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64708
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9H9Q2
Gene Symbols: COPS7B
Immunogen: Between 225 and C-term
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CSN7b
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
COPS7B
Gene Alias:
COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 7B, COP9 constitutive photomorphogenic homolog subunit 7B, COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis), CSN7B, JAB1-containing signalosome subunit 7b, SGN7b, signalosome subunit 7b
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64708
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9H9Q2
Gene Symbols:
COPS7B
Immunogen:
Between 225 and C-term
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CSN7b
Classification: Polyclonal
Conjugate: Unconjugated
Gene: COPS7B
Gene Alias: COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 7B, COP9 constitutive photomorphogenic homolog subunit 7B, COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis), CSN7B, JAB1-containing signalosome subunit 7b, SGN7b, signalosome subunit 7b
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64708
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q9H9Q2
Gene Symbols: COPS7B
Immunogen: Between 225 and C-term
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CSN7b
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
COPS7B
Gene Alias:
COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 7B, COP9 constitutive photomorphogenic homolog subunit 7B, COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis), CSN7B, JAB1-containing signalosome subunit 7b, SGN7b, signalosome subunit 7b
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64708
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q9H9Q2
Gene Symbols:
COPS7B
Immunogen:
Between 225 and C-term
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG