50-155-6861

H2AX Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-155-6861-Each-of-1 In Stock ₹ 41,863.65

50-155-6861 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

H2AX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

H2AFX

Gene Alias

H2A/X, H2AX, H2AX histone, histone H2AX

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15270, 3014

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

P16104, P27661

Gene Symbols

H2AFX

Immunogen

C-terminus

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bethyl Laboratories, Inc

50-155-6857

--

Img

Bethyl Laboratories, Inc

50-155-6859

--

Img

Bethyl Laboratories, Inc

50-155-6772

--

Img

Bethyl Laboratories, Inc

50-155-7593

--

Img

Bethyl Laboratories, Inc

50-155-6759

--

Img

Bethyl Laboratories, Inc

50-155-6949

--

Img

Bethyl Laboratories, Inc

50-155-6769

--

Img

Bethyl Laboratories, Inc

50-155-7651

--

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
  • In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
  • The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
  • The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
  • Structurally, H2A.x contains 143 amino acid residues
  • Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
  • There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
  • The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
  • Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
  • Histone H2A.x contributes to histone-formation and therefore the structure of DNA
  • Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-6861

--


Antigen:
H2AX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AFX

Gene Alias:
H2A/X, H2AX, H2AX histone, histone H2AX

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15270, 3014

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P16104, P27661

Gene Symbols:
H2AFX

Immunogen:
C-terminus

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-6865

--


Antigen:
BID

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bid

Gene Alias:
FP497, MGC15319, MGC42355

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12122

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P70444

Gene Symbols:
Bid

Immunogen:
Between 1 and 50

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-6866

--


Antigen:
MLL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KMT2A

Gene Alias:
ALL-1; Trithorax-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4297

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q03164

Gene Symbols:
KMT2A

Immunogen:
Between 720 and 780

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-6868

--


Antigen:
MLL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KMT2A

Gene Alias:
ALL-1; Trithorax-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4297

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q03164

Gene Symbols:
KMT2A

Immunogen:
Between 720 and 780

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG