50-155-7259

KAP-1 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-155-7259-Each-of-1 In Stock ₹ 41,863.65

50-155-7259 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

KAP-1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TRIM28

Gene Alias

Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10155, 21849

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

Q13263, Q62318

Gene Symbols

Trim28

Immunogen

Between 1 and 50

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For ICC, formaldehyde fixation is recommended
  • Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells
  • For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • The KRAB (Kruppel-associated box) domain is about 45 amino acids in length and is a transcriptional repression domain found in numerous transcription factors
  • There have been identified over 220 KRAB-zinc finger protein (KRAB-ZFP) genes in the human genome
  • These proteins functionally repress transcription via specific interactions with KAP-1 (KRAB-associated protein 1)
  • KAP-1 is an 835 amino acid polypeptide that contains a RING finger, B boxes, and a PHD finger
  • KAP-1 has been shown to form complexes with KRAB-domain transcription factors and increase the efficiency with which they mediate repression
  • KAP-1 has also been shown to directly interact with HP1 (heterochromatin protein 1) and KRAZ1 (Kruppel-associated box-containing zinc finger protein 1)
  • KAP-1 directly targets KRAZ1 to the foci of centromeric heterochromatin containing HP1alpha, thus helping to regulate transcriptional repression
  • Studies have shown that KAP-1 mutants with the ability to bind KRAB but unable to bind HP1 leads to random distribution of KRAZ1 and strong transcriptional activation.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-7259

--


Antigen:
KAP-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM28

Gene Alias:
Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10155, 21849

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q13263, Q62318

Gene Symbols:
Trim28

Immunogen:
Between 1 and 50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7261

--


Antigen:
KAP-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM28

Gene Alias:
Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10155, 21849

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q13263, Q62318

Gene Symbols:
TRIM28

Immunogen:
Between 1 and 50

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7262

--


Antigen:
KAP-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM28

Gene Alias:
Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10155, 21849

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q13263, Q62318

Gene Symbols:
TRIM28

Immunogen:
Between 650 and 700

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7265

--


Antigen:
PCNA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PCNA

Gene Alias:
ATLD2, cyclin, DNA polymerase delta auxiliary protein, PCNA

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18538, 5111

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P12004, P17918

Gene Symbols:
PCNA

Immunogen:
Between 75 and 125

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG