50-155-7535

Nanog Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-155-7535-Each-of-1 In Stock ₹ 11,905.67

50-155-7535 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

og

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

Q80Z64

Gene Symbols

og

Immunogen

Between 250 and C-term

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

og

Gene Alias

2410002E02Rik, early embryo specific expression NK family, early embryo specific expression NK-type homeobox protein, ecat4, ENK, ES cell-associated protein 4, homeobox transcription factor og

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

71950

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • NANOG (og homeobox) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells
  • NANOG mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells
  • Human NANOG protein shares 52% overall amino acid identity with the mouse protein, and 85% identity in the homeodomain
  • Human NANOG maps to gene locus 12p13.31, while the mouse NANOG maps to gene loci 6 F2
  • Murine embryonic NANOG expression is detected in the inner cell mass of the blastocyst
  • Research studies have shown that high levels of human NANOG expression in the undifferentiated N-Tera embryonal carcinoma cell line
  • Further, NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal
  • The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases
  • Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts
  • Experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine
  • When overexpressed, NANOG promotes cells to enter into S phase and proliferation
  • Diseases associated with dysfunction in the NANOG protein include tetracarcinoma and germ cell/embryonal cancer.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-7535

--


Antigen:
og

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q80Z64

Gene Symbols:
og

Immunogen:
Between 250 and C-term

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
og

Gene Alias:
2410002E02Rik, early embryo specific expression NK family, early embryo specific expression NK-type homeobox protein, ecat4, ENK, ES cell-associated protein 4, homeobox transcription factor og

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
71950

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-7539

--


Antigen:
LOK

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
O94804

Gene Symbols:
STK10

Immunogen:
Between 900 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
STK10

Gene Alias:
Serine/threonine protein kinase 10; Lymphocyte-oriented kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6793

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-7542

--


Antigen:
SNX1

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q13596

Gene Symbols:
SNX1

Immunogen:
Between 475 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
SNX1

Gene Alias:
HsT17379, MGC8664, SNX1A, Vps5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6642

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-7544

--


Antigen:
G6PD

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P11413, Q00612

Gene Symbols:
G6PD, G6pdx

Immunogen:
Between 50 and 100

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
G6PD

Gene Alias:
G6PD1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14381, 2539

Content And Storage:
4° C

Form:
Liquid