50-155-7685

TSC2 Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-155-7685-Each-of-1 In Stock ₹ 11,905.67

50-155-7685 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

TSC2

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

P49815

Gene Symbols

TSC2

Immunogen

Between 1750 and C-term

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

TSC2

Gene Alias

Tuberin; Tuberous sclerosis 2 protein; TSC2; TSC4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7249

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
  • Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
  • TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • Interaction between TSC1 and TSC2 may facilitate vesicular docking
  • TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
  • Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
  • Alternative splicing results in transcript variants of three different isoforms of TSC2.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-7685

--


Antigen:
TSC2

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P49815

Gene Symbols:
TSC2

Immunogen:
Between 1750 and C-term

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
Tuberin; Tuberous sclerosis 2 protein; TSC2; TSC4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7249

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-7686

--


Antigen:
HDAC3

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O15379, O88895

Gene Symbols:
HDAC3

Immunogen:
Between 375 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
HDAC3

Gene Alias:
Histone Deacetylase 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15183, 8841

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-7693

--


Antigen:
MST2/STK3

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q13188

Gene Symbols:
STK3

Immunogen:
Between 400 and 450

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
STK3

Gene Alias:
MST-2; STE20-like kinase MST2; mammalian STE20-like protein kinase 2; serine/threonine kinase 3 (STE20 homolog, yeast); serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine-protein kinase 3; serine/threonine-protein kinase Krs-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6788

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-7694

--


Antigen:
MST1-2/STK3-4

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q13043, Q9JI10, Q13188, Q9JI11

Gene Symbols:
STK3, STK4

Immunogen:
C-terminus

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
STK3

Gene Alias:
MST-2; STE20-like kinase MST2; mammalian STE20-like protein kinase 2; serine/threonine kinase 3 (STE20 homolog, yeast); serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine-protein kinase 3; serine/threonine-protein kinase Krs-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56274, 58231, 6788, 6789

Content And Storage:
4° C

Form:
Liquid