50-155-7721

LATS1 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-155-7721-Each-of-1 In Stock ₹ 41,863.65

50-155-7721 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

LATS1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LATS1

Gene Alias

LATS (large tumor suppressor, Drosophila) homolog 1; WARTS protein kinase; h-warts; large tumor suppressor homolog 1; serine/threonine-protein kinase LATS1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16798, 9113

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

O95835, Q8BYR2

Gene Symbols

LATS1

Immunogen

Between 1075 and C-term

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • LATS1 is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis
  • The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase
  • The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A
  • In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding
  • Biochemical and genetic data suggest a role as a tumor suppressor
  • This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-7721

--


Antigen:
LATS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LATS1

Gene Alias:
LATS (large tumor suppressor, Drosophila) homolog 1; WARTS protein kinase; h-warts; large tumor suppressor homolog 1; serine/threonine-protein kinase LATS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16798, 9113

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
O95835, Q8BYR2

Gene Symbols:
LATS1

Immunogen:
Between 1075 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7727

--


Antigen:
KPNB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KPNB1

Gene Alias:
NTF97, Karyopherin, Importin Beta, Nuclear Transport Factor p97, karyopherin beta 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16211, 3837

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P70168, Q14974

Gene Symbols:
KPNB1

Immunogen:
Between 825 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7729

--


Antigen:
KPNB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KPNB1

Gene Alias:
NTF97, Karyopherin, Importin Beta, Nuclear Transport Factor p97, karyopherin beta 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16211, 3837

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P70168, Q14974

Gene Symbols:
Kpnb1

Immunogen:
Between 825 and C-term

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-7730

--


Antigen:
RCH1/KPNA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KPNA2

Gene Alias:
IPOA1, QIP2, RCH1, SRP1alpha

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3838

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P52292

Gene Symbols:
KPNA2

Immunogen:
Between 1 and 50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG