50-155-8342

Cul4a Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-155-8342-Each-of-1 In Stock ₹ 41,863.65

50-155-8342 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

Cul4a

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CUL4A

Gene Alias

Cullin-4A; CUL-4A; CUL4A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8451, 99375

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

Q13619, Q3TCH7

Gene Symbols

Cul4a

Immunogen

Between 700 and C-term

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • CUL4a is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediates the ubiquitination and subsequent proteasomal degradation of target proteins
  • As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
  • The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1
  • The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component
  • DCX(DET1-COP1) directs ubiquitination of JUN
  • DCX(DDB2) directs ubiquitination of XPC
  • In association with RBX1, DDB1 and DDB2 is required for histone H3 and histone H4 ubiquitination in response to ultraviolet and may be important for subsequent DNA repair
  • DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitiantion of TP53 in response to radiation-induced DNA damage and during DNA replication
  • In association with DDB1 and SKP2 probably is involved in ubiquitination of CDKN1B/p27kip
  • Is involved in ubiquitination of HOXA9.

Compare Similar Items

Show Difference

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Bethyl Laboratories, Inc

50-155-8342

--


Antigen:
Cul4a

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CUL4A

Gene Alias:
Cullin-4A; CUL-4A; CUL4A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8451, 99375

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q13619, Q3TCH7

Gene Symbols:
Cul4a

Immunogen:
Between 700 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8345

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Antigen:
RPL7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPL7

Gene Alias:
60S ribosomal protein L7, RPL7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19989, 6129

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P14148, P18124

Gene Symbols:
Rpl7

Immunogen:
Between 75 and 125

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8348

--


Antigen:
RPL7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPL7

Gene Alias:
60S ribosomal protein L7, RPL7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19989, 6129

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P14148, P18124

Gene Symbols:
RPL7

Immunogen:
Between 200 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8350

--


Antigen:
RPL7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPL7

Gene Alias:
60S ribosomal protein L7, RPL7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19989, 6129

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P14148, P18124

Gene Symbols:
RPL7

Immunogen:
Between 200 and C-term

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG