50-155-8482

SUPT6H Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-155-8482-Each-of-1 In Stock ₹ 41,863.65

50-155-8482 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

SUPT6H

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SUPT6H

Gene Alias

KIAA0162, MGC87943, SPT6, SPT6H, emb-5, hSPT6; tat-CT2 protein; tat-cotransactivator 2 protein; transcription elongation factor SPT6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20926, 6830

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.2 mg/ml

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

Q62383, Q7KZ85

Gene Symbols

Supt6, SUPT6H

Immunogen

Between 1050 and 1100

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Bethyl Laboratories, Inc

50-155-8481

--

Img

Bethyl Laboratories, Inc

50-155-8479

--

Img

Bethyl Laboratories, Inc

50-155-8485

--

Img

Bethyl Laboratories, Inc

50-155-7982

--

Img

Bethyl Laboratories, Inc

50-155-8439

--

Img

Bethyl Laboratories, Inc

50-155-9327

--

Img

Bethyl Laboratories, Inc

50-155-8837

--

Img

Bethyl Laboratories, Inc

50-155-8014

--

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Based on 100% sequence identity, this antibody is predicted to react with D
  • melanogaster and Zebrafish Transcription elongation factor which binds histone H3 and plays a key role in the regulation of transcription elongation and mRNA processing
  • Enhances the transcription elongation by RNA polymerase II (RNAPII) and is also required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat
  • Besides chaperoning histones in transcription, acts to transport and splice mRNA by forming a complex with IWS1 and the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A)
  • The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2), to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription
  • SUPT6H via its association with SETD1A, regulates both class-switch recombination and somatic hypermutation through formation of H3K4me3 epigenetic marks on activation-induced cytidine deaminase (AICDA) target loci
  • Promotes the activation of the myogenic gene program by entailing erasure of the repressive H3K27me3 epigenetic mark through stabilization of the chromatin interaction of the H3K27 demethylase KDM6A.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-8482

--


Antigen:
SUPT6H

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SUPT6H

Gene Alias:
KIAA0162, MGC87943, SPT6, SPT6H, emb-5, hSPT6; tat-CT2 protein; tat-cotransactivator 2 protein; transcription elongation factor SPT6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20926, 6830

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q62383, Q7KZ85

Gene Symbols:
Supt6, SUPT6H

Immunogen:
Between 1050 and 1100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8485

--


Antigen:
SUPT6H

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SUPT6H

Gene Alias:
KIAA0162, MGC87943, SPT6, SPT6H, emb-5, hSPT6; tat-CT2 protein; tat-cotransactivator 2 protein; transcription elongation factor SPT6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6830

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q7KZ85

Gene Symbols:
SUPT6H

Immunogen:
Between 1553 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8487

--


Antigen:
CASC5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KNL1

Gene Alias:
Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57082

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q8NG31

Gene Symbols:
KNL1

Immunogen:
Between 250 and 300

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-8488

--


Antigen:
CASC5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KNL1

Gene Alias:
Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57082

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q8NG31

Gene Symbols:
KNL1

Immunogen:
Between 250 and 300

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG