50-155-8857
DTL/CDT2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-8857-Each-of-1 | In Stock | ₹ 41,863.65 |
50-155-8857 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
DTL/CDT2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DTL
Gene Alias
CDT2, DCAF2, L2DTL, RAMP, DDB1 and CUL4 associated factor 2, DDB1- and CUL4-associated factor 2, RA regulated nuclear matrix associated protein, RA-regulated nuclear matrix-associated protein, denticleless protein homolog, lethal(2) denticleless protein homolog, retinoic acid-regulated
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51514
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Immunoprecipitation
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q9NZJ0
Gene Symbols
DTL
Immunogen
Between 375 and 425
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections
- Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis
- The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1)
- CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication
- CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing
- Most substrates require their interaction with PCNA for their polyubiquitination: substrates interact with PCNA via their PIP-box, and those containing the ′K+4′ motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation
- In undamaged proliferating cells, the DCX(DTL) complex also promotes the ′Lys-164′ monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis.
Compare Similar Items
Show Difference
Antigen: DTL/CDT2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DTL
Gene Alias: CDT2, DCAF2, L2DTL, RAMP, DDB1 and CUL4 associated factor 2, DDB1- and CUL4-associated factor 2, RA regulated nuclear matrix associated protein, RA-regulated nuclear matrix-associated protein, denticleless protein homolog, lethal(2) denticleless protein homolog, retinoic acid-regulated
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51514
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Immunoprecipitation
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9NZJ0
Gene Symbols: DTL
Immunogen: Between 375 and 425
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DTL/CDT2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DTL
Gene Alias:
CDT2, DCAF2, L2DTL, RAMP, DDB1 and CUL4 associated factor 2, DDB1- and CUL4-associated factor 2, RA regulated nuclear matrix associated protein, RA-regulated nuclear matrix-associated protein, denticleless protein homolog, lethal(2) denticleless protein homolog, retinoic acid-regulated
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51514
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9NZJ0
Gene Symbols:
DTL
Immunogen:
Between 375 and 425
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DTL/CDT2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DTL
Gene Alias: CDT2, DCAF2, L2DTL, RAMP, DDB1 and CUL4 associated factor 2, DDB1- and CUL4-associated factor 2, RA regulated nuclear matrix associated protein, RA-regulated nuclear matrix-associated protein, denticleless protein homolog, lethal(2) denticleless protein homolog, retinoic acid-regulated
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51514, 76843
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 0.2 mg/ml
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q3TLR7, Q9NZJ0
Gene Symbols: Dtl
Immunogen: Between 680 and C-term
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
DTL/CDT2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DTL
Gene Alias:
CDT2, DCAF2, L2DTL, RAMP, DDB1 and CUL4 associated factor 2, DDB1- and CUL4-associated factor 2, RA regulated nuclear matrix associated protein, RA-regulated nuclear matrix-associated protein, denticleless protein homolog, lethal(2) denticleless protein homolog, retinoic acid-regulated
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51514, 76843
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
0.2 mg/ml
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q3TLR7, Q9NZJ0
Gene Symbols:
Dtl
Immunogen:
Between 680 and C-term
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Topo II Beta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOP2B
Gene Alias: TOPIIB, top2beta
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7155
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration: 0.2 mg/ml
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q02880
Gene Symbols: TOP2B
Immunogen: Between 1475 and 1525
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Topo II Beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOP2B
Gene Alias:
TOPIIB, top2beta
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7155
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Concentration:
0.2 mg/ml
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q02880
Gene Symbols:
TOP2B
Immunogen:
Between 1475 and 1525
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Topo II Beta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOP2B
Gene Alias: TOPIIB, top2beta
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7155
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q02880
Gene Symbols: TOP2B
Immunogen: Between 1475 and 1525
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Topo II Beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOP2B
Gene Alias:
TOPIIB, top2beta
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7155
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q02880
Gene Symbols:
TOP2B
Immunogen:
Between 1475 and 1525
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG