50-155-9081

SMARCC2/BAF170 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-155-9081-Each-of-1 In Stock ₹ 41,863.65

50-155-9081 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

SMARCC2/BAF170

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SMARCC2

Gene Alias

BAF170, CRACC2, DKFZp313D0632, Rsc8, BRG1-associated factor 170; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein; chromatin remodeling complex BAF170 subunit; mammalian chromatin remodeling complex BRG1-associated factor 170

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6601, 68094

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

Q6PDG5, Q8TAQ2

Gene Symbols

Smarcc2

Immunogen

Between 575 and 625

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology)
  • Can stimulate the ATPase activity of the catalytic subunit of these complexes
  • May be required for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells
  • Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene
  • Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex)
  • During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state
  • The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes
  • As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF)
  • The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells
  • The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth .

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-9081

--


Antigen:
SMARCC2/BAF170

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMARCC2

Gene Alias:
BAF170, CRACC2, DKFZp313D0632, Rsc8, BRG1-associated factor 170; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein; chromatin remodeling complex BAF170 subunit; mammalian chromatin remodeling complex BRG1-associated factor 170

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6601, 68094

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q6PDG5, Q8TAQ2

Gene Symbols:
Smarcc2

Immunogen:
Between 575 and 625

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9083

--


Antigen:
SMARCC2/BAF170

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMARCC2

Gene Alias:
BAF170, CRACC2, DKFZp313D0632, Rsc8, BRG1-associated factor 170; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein; chromatin remodeling complex BAF170 subunit; mammalian chromatin remodeling complex BRG1-associated factor 170

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6601, 68094

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q6PDG5, Q8TAQ2

Gene Symbols:
SMARCC2

Immunogen:
Between 575 and 625

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9084

--


Antigen:
SMARCC2/BAF170

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMARCC2

Gene Alias:
BAF170, CRACC2, DKFZp313D0632, Rsc8, BRG1-associated factor 170; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein; chromatin remodeling complex BAF170 subunit; mammalian chromatin remodeling complex BRG1-associated factor 170

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6601, 68094

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q6PDG5, Q8TAQ2

Gene Symbols:
Smarcc2

Immunogen:
Between 1164 and C-term

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9087

--


Antigen:
ARID1A/BAF250

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARID1A

Gene Alias:
BAF250, C1orf4, AT rich interactive domain 1A SWI-like, B120, P270, SMARCF1, ELD, OSA1, hELD, hOSA1, BAF250a, MRD14, BM029

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8289

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O14497

Gene Symbols:
ARID1A

Immunogen:
Between 675 and 725

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG