50-155-9835
BRF1 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-155-9835-Each-of-1 | In Stock | ₹ 12,384.35 |
50-155-9835 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
BRF1
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
Q8CFK2, Q92994
Gene Symbols
Brf1
Immunogen
Between 627 and 677
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Gene
BRF1
Gene Alias
Transcription factor IIIB 90 kDa subunit, TFIIIB90, hTFIIIB90, B-related factor 1, BRF-1, hBRF, TAF3B2, TATA box-binding protein-associated factor, RNA polymerase III, subunit 2, BRF1, BRF, GTF3B, TAF3B2, TAF3C
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2972, 72308
Content And Storage
4° C
Form
Liquid
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division
- Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes
- The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in maligt cells in vivo, such as ovarian carcinomas
- TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of maligt cells
- The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (TFIIIB90, BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells
- In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.
Compare Similar Items
Show Difference
Antigen: BRF1
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q8CFK2, Q92994
Gene Symbols: Brf1
Immunogen: Between 627 and 677
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Gene: BRF1
Gene Alias: Transcription factor IIIB 90 kDa subunit, TFIIIB90, hTFIIIB90, B-related factor 1, BRF-1, hBRF, TAF3B2, TATA box-binding protein-associated factor, RNA polymerase III, subunit 2, BRF1, BRF, GTF3B, TAF3B2, TAF3C
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2972, 72308
Content And Storage: 4° C
Form: Liquid
Antigen:
BRF1
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q8CFK2, Q92994
Gene Symbols:
Brf1
Immunogen:
Between 627 and 677
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Gene:
BRF1
Gene Alias:
Transcription factor IIIB 90 kDa subunit, TFIIIB90, hTFIIIB90, B-related factor 1, BRF-1, hBRF, TAF3B2, TATA box-binding protein-associated factor, RNA polymerase III, subunit 2, BRF1, BRF, GTF3B, TAF3B2, TAF3C
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2972, 72308
Content And Storage:
4° C
Form:
Liquid
Antigen: PolH
Classification: Polyclonal
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9Y253
Gene Symbols: POLH
Immunogen: Between 640 and 690
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation
Conjugate: Unconjugated
Gene: POLH
Gene Alias: RAD30, RAD30A, XP-V, XPV, DNA polymerase eta, RAD30 homolog A, xeroderma pigmentosum variant type protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5429
Content And Storage: 4° C
Form: Liquid
Antigen:
PolH
Classification:
Polyclonal
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9Y253
Gene Symbols:
POLH
Immunogen:
Between 640 and 690
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation
Conjugate:
Unconjugated
Gene:
POLH
Gene Alias:
RAD30, RAD30A, XP-V, XPV, DNA polymerase eta, RAD30 homolog A, xeroderma pigmentosum variant type protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5429
Content And Storage:
4° C
Form:
Liquid
Antigen: PolH
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q9Y253
Gene Symbols: POLH
Immunogen: Between 690 and 713
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: POLH
Gene Alias: RAD30, RAD30A, XP-V, XPV, DNA polymerase eta, RAD30 homolog A, xeroderma pigmentosum variant type protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5429
Content And Storage: 4° C
Form: Liquid
Antigen:
PolH
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q9Y253
Gene Symbols:
POLH
Immunogen:
Between 690 and 713
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
POLH
Gene Alias:
RAD30, RAD30A, XP-V, XPV, DNA polymerase eta, RAD30 homolog A, xeroderma pigmentosum variant type protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5429
Content And Storage:
4° C
Form:
Liquid
Antigen: RBM13
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q9BXY0
Gene Symbols: MAK16
Immunogen: Between 250 and 300
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: MAK16
Gene Alias: MAK16 homolog (S. cerevisiae), MAK16L, NNP78, Protein RBM13, RBM13, RNA binding motif protein 13, RNA binding protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84549
Content And Storage: 4° C
Form: Liquid
Antigen:
RBM13
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q9BXY0
Gene Symbols:
MAK16
Immunogen:
Between 250 and 300
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
MAK16
Gene Alias:
MAK16 homolog (S. cerevisiae), MAK16L, NNP78, Protein RBM13, RBM13, RNA binding motif protein 13, RNA binding protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84549
Content And Storage:
4° C
Form:
Liquid