50-155-9853

GTF3C3/TFIIIC102 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-155-9853-Each-of-1 In Stock ₹ 41,863.65

50-155-9853 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

GTF3C3/TFIIIC102

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GTF3C3

Gene Alias

General transcription factor 3C polypeptide 3, Transcription factor IIIC 102 kDa subunit, TFIIIC 102 kDa subunit, TFIIIC102, Transcription factor IIIC subunit gamma, TF3C-gamma, GTF3C3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9330

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

Q9Y5Q9

Gene Symbols

GTF3C3

Immunogen

Between 100 and 150

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • RNA polymerase (pol) III synthesizes tRNA, 5s rRNA, 7SL RNA and U6 snRNA and is overexpressed in many transformed cell lines and tumors in vivo, since cells must duplicate its protein components before division
  • Therefore, in order to maintain rapid growth, cells must produce a high level of Pol III transcribed RNA, which requires the presence of the TFIIIB and TFIIIC2 transcription factor complexes
  • The TFIIIC2 complex is composed of five subunits, TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, that are overexpressed in adenovirus transformed cells as well as in maligt cells in vivo, such as ovarian carcinomas
  • TFIIIC2 recruits RNA pol III and TFIIIB to promoter elements and may be a key component in the deregulation of maligt cells
  • The TFIIIB complex includes the TATA-binding protein (TBP), TFIIB-related factor 1 (BRF1) and TFIIIB, the expression of which are also upregulated in transformed cells
  • In many carcinomas, the tumor suppressors retinoblastoma (RB) and p53 are inactivated, which affects their ability to bind and inactivate the function of TFIIIB.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-155-9853

--


Antigen:
GTF3C3/TFIIIC102

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTF3C3

Gene Alias:
General transcription factor 3C polypeptide 3, Transcription factor IIIC 102 kDa subunit, TFIIIC 102 kDa subunit, TFIIIC102, Transcription factor IIIC subunit gamma, TF3C-gamma, GTF3C3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9330

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9Y5Q9

Gene Symbols:
GTF3C3

Immunogen:
Between 100 and 150

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9861

--


Antigen:
GTF3C4/TFIIIC90

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTF3C4

Gene Alias:
KAT12, TFIII90, TFIIIC290, TFIIIC90, TFIIICDELTA, TF3C-delta, TFIIIC 90 kDa subunit, general transcription factor 3C 4, general transcription factor 3C polypeptide 4, transcription factor IIIC 90 kDa subunit, transcription factor IIIC subunit delta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9329

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9UKN8

Gene Symbols:
GTF3C4

Immunogen:
Between 625 and 675

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9862

--


Antigen:
GTF3C4/TFIIIC90

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTF3C4

Gene Alias:
KAT12, TFIII90, TFIIIC290, TFIIIC90, TFIIICDELTA, TF3C-delta, TFIIIC 90 kDa subunit, general transcription factor 3C 4, general transcription factor 3C polypeptide 4, transcription factor IIIC 90 kDa subunit, transcription factor IIIC subunit delta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9329

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9UKN8

Gene Symbols:
GTF3C4

Immunogen:
Between 625 and 675

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-155-9865

--


Antigen:
GTF3C5/TFIIIC63

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GTF3C5

Gene Alias:
general transcription factor IIIC, polypeptide 5 (63kD), general transcription factor IIIC, polypeptide 5, 63kDa, TF3C-epsilon, TFIIIC 63 kDa subunit, TFiiiC2-63, TFIIIC63, TFIIICepsilon, transcription factor IIIC 63 kDa subunit, transcription factor IIIC subunit epsilon, transcription factor IIIC, 63 kD

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
70239, 9328

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q8R2T8, Q9Y5Q8

Gene Symbols:
Gtf3c5

Immunogen:
Between 469 and 519

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG