50-155-9902

ABRO Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-155-9902-Each-of-1 In Stock ₹ 11,905.67

50-155-9902 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

ABRO

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

Q15018

Gene Symbols

ABRAXAS2

Immunogen

Between 350 and 390

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

ABRAXAS2

Gene Alias

Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23172

Content And Storage

4° C

Form

Liquid

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Component of the BRISC complex, a multiprotein complex that specifically cleaves ′Lys-63′-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates (PubMed:19214193, PubMed:20032457, PubMed:20656690, PubMed:24075985)
  • May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (PubMed:20656690)
  • Plays a role in regulating the onset of apoptosis via its role in modulating ′Lys-63′-linked ubiquitination of target proteins
  • Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed:26195665)
  • Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression (PubMed:24075985, PubMed:26344097)
  • Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed:24075985)
  • Required for normal induction of p53/TP53 in response to DNA damage (PubMed:25283148)
  • Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage (PubMed:25283148).

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Bethyl Laboratories, Inc

50-155-9902

--


Antigen:
ABRO

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q15018

Gene Symbols:
ABRAXAS2

Immunogen:
Between 350 and 390

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
ABRAXAS2

Gene Alias:
Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23172

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-9903

--


Antigen:
ABRO

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q15018

Gene Symbols:
ABRAXAS2

Immunogen:
Between 390 and 415

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Gene:
ABRAXAS2

Gene Alias:
Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23172

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-9904

--


Antigen:
ABRO

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q15018

Gene Symbols:
ABRAXAS2

Immunogen:
Between 390 and 415

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Gene:
ABRAXAS2

Gene Alias:
Abraxas brother, abraxas brother 1, abraxas brother protein 1, ABRO1, Em:AC068896.4, family with sequence similarity 175, member B, KIAA0157, Protein FAM175B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23172

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-155-9905

--


Antigen:
TLK2

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q86UE8

Gene Symbols:
TLK2

Immunogen:
Between 722 and 772

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
TLK2

Gene Alias:
Serine/threonine-protein kinase tousled-like 2, Tousled-like kinase 2, PKU-alpha

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11011

Content And Storage:
4° C

Form:
Liquid