50-156-0230

BRCA1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-0230-Each-of-1 In Stock ₹ 11,905.67

50-156-0230 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

BRCA1

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

P38398

Gene Symbols

BRCA1

Immunogen

Between 700 and 750

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

BRCA1

Gene Alias

Breast Cancer 1, Breast Cancer 1 Early Onset, Breast Ovarian Cancer Susceptibility, IRIS, Papillary Serous Carcinoma Of The Peritoneum, PSCP, RNF53

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

672

Content And Storage

4° C

Form

Liquid

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee BRCA1 (breast and ovarian cancer susceptibility protein 1) is a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor in combination with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC (for BRCA1 associated genome surveillance complex)
  • BRCA1 associates with RNA polymerase II, and through the C terminal domain, also interacts with histone deacetylase complex
  • The BRCA1 protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
  • Mutations in the BRCA1 gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
  • Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
  • Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
  • A related pseudogene, which is also located on chromosome 17, has been identified.

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Bethyl Laboratories, Inc

50-156-0230

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Antigen:
BRCA1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P38398

Gene Symbols:
BRCA1

Immunogen:
Between 700 and 750

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
BRCA1

Gene Alias:
Breast Cancer 1, Breast Cancer 1 Early Onset, Breast Ovarian Cancer Susceptibility, IRIS, Papillary Serous Carcinoma Of The Peritoneum, PSCP, RNF53

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
672

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-0231

--


Antigen:
AKAP1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q92667

Gene Symbols:
AKAP1

Immunogen:
Between 375 and 425

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
AKAP1

Gene Alias:
AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, A-kinase anchor protein 1, mitochondrial, A-kinase anchor protein 149 kDa, AKAP 149, D-AKAP-1, dual-specificity A-kinase anchoring protein 1, protein kinase A anchoring protein 1, protein kinase A1, protein phosphatase 1, regulatory subunit 43, spermatid A-kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8165

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-0233

--


Antigen:
AKAP1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q92667

Gene Symbols:
AKAP1

Immunogen:
Between 375 and 425

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
AKAP1

Gene Alias:
AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, A-kinase anchor protein 1, mitochondrial, A-kinase anchor protein 149 kDa, AKAP 149, D-AKAP-1, dual-specificity A-kinase anchoring protein 1, protein kinase A anchoring protein 1, protein kinase A1, protein phosphatase 1, regulatory subunit 43, spermatid A-kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8165

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-0234

--


Antigen:
AKAP1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q92667

Gene Symbols:
AKAP1

Immunogen:
Between 450 and 500

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
AKAP1

Gene Alias:
AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, A-kinase anchor protein 1, mitochondrial, A-kinase anchor protein 149 kDa, AKAP 149, D-AKAP-1, dual-specificity A-kinase anchoring protein 1, protein kinase A anchoring protein 1, protein kinase A1, protein phosphatase 1, regulatory subunit 43, spermatid A-kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8165

Content And Storage:
4° C

Form:
Liquid