HCF1 Polyclonal Antibody, Bethyl Laboratories

Description

• The recommended shelf life for this product is 1 year from date of receipt
• This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal
• This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain
• The final form of this protein consists of noncovalently bound N- and C-terminal chains
• The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection
• Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.