Symplekin Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Description

• The recommended shelf life for this product is 1 year from date of receipt
• Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
• SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression
• The protein forms a high-molecular weight complex with components of the polyadenylation machinery
• It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex
• It also participates in 3′-end maturation of histone mRNAs, which do not undergo polyadenylation
• The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types.This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression
• The protein forms a high-molecular weight complex with components of the polyadenylation machinery
• It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex
• It also participates in 3′-end maturation of histone mRNAs, which do not undergo polyadenylation
• The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types
• Publication Note: This RefSeq record includes a subset of the publications that are available for this gene
• Please see the Entrez Gene record to access additional publications.