50-156-1314
TAK1 Polyclonal Antibody, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-1314-Each-of-1 | In Stock | ₹ 12,384.35 |
50-156-1314 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,384.35
GST (18%): ₹ 2,229.183
Total Price: ₹ 14,613.533
Antigen
TAK1
Classification
Polyclonal
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.
O43318
Gene Symbols
MAP3K7
Immunogen
Between 450 and 500
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
MAP3K7
Gene Alias
MEKK7, TAK1, TGF1a
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6885
Content And Storage
4° C
Form
Liquid
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
- Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
- It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
- Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
- TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
- Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
- In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
- Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan.
Compare Similar Items
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Antigen: TAK1
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: O43318
Gene Symbols: MAP3K7
Immunogen: Between 450 and 500
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: MAP3K7
Gene Alias: MEKK7, TAK1, TGF1a
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6885
Content And Storage: 4° C
Form: Liquid
Antigen:
TAK1
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
O43318
Gene Symbols:
MAP3K7
Immunogen:
Between 450 and 500
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
MAP3K7
Gene Alias:
MEKK7, TAK1, TGF1a
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6885
Content And Storage:
4° C
Form:
Liquid
Antigen: HPK1
Classification: Polyclonal
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q92918
Gene Symbols: MAP4K1
Immunogen: Between 1 and 50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: MAP4K1
Gene Alias: MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1; HPK1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11184
Content And Storage: 4° C
Form: Liquid
Antigen:
HPK1
Classification:
Polyclonal
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q92918
Gene Symbols:
MAP4K1
Immunogen:
Between 1 and 50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
MAP4K1
Gene Alias:
MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1; HPK1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11184
Content And Storage:
4° C
Form:
Liquid
Antigen: HPK1
Classification: Polyclonal
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q92918
Gene Symbols: MAP4K1
Immunogen: Between 550 and 600
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation
Conjugate: Unconjugated
Gene: MAP4K1
Gene Alias: MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1; HPK1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11184
Content And Storage: 4° C
Form: Liquid
Antigen:
HPK1
Classification:
Polyclonal
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q92918
Gene Symbols:
MAP4K1
Immunogen:
Between 550 and 600
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation
Conjugate:
Unconjugated
Gene:
MAP4K1
Gene Alias:
MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1; HPK1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11184
Content And Storage:
4° C
Form:
Liquid
Antigen: HPK1
Classification: Polyclonal
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q92918
Gene Symbols: MAP4K1
Immunogen: Between 550 and 600
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation
Conjugate: Unconjugated
Gene: MAP4K1
Gene Alias: MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1; HPK1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11184
Content And Storage: 4° C
Form: Liquid
Antigen:
HPK1
Classification:
Polyclonal
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q92918
Gene Symbols:
MAP4K1
Immunogen:
Between 550 and 600
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation
Conjugate:
Unconjugated
Gene:
MAP4K1
Gene Alias:
MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1; HPK1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11184
Content And Storage:
4° C
Form:
Liquid