50-156-1969

JAK2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-156-1969-Each-of-1 In Stock ₹ 41,863.65

50-156-1969 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

JAK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

Between 1082 and 1132

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Based on 100% sequence identity, this antibody is predicted to react with Orangutan Janus Activating Kinase 2 (JAK2) is a non-rececptor tyrosine kinase involved in various processes such as cell growth, development, differentiation, and histone modifications
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting this gene can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

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Img

Bethyl Laboratories, Inc

50-156-1969

--


Antigen:
JAK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
Between 1082 and 1132

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-1972

--


Antigen:
TOPORS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TOPORS

Gene Alias:
LUN, p53-binding protein 3, P53BP3, retinitis pigmentosa 31 (autosomal domit), RP31, SUMO1-protein E3 ligase Topors, topoisomerase I binding, arginine/serine-rich, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, Topoisomerase I-binding arginine/serine-rich protein, topoisomerase I-binding RING finger protein, TP53BPL, tumor suppressor p53-binding protein 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10210

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9NS56

Gene Symbols:
TOPORS

Immunogen:
Between 995 and 1045

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-1974

--


Antigen:
TOPORS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TOPORS

Gene Alias:
LUN, p53-binding protein 3, P53BP3, retinitis pigmentosa 31 (autosomal domit), RP31, SUMO1-protein E3 ligase Topors, topoisomerase I binding, arginine/serine-rich, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase, Topoisomerase I-binding arginine/serine-rich protein, topoisomerase I-binding RING finger protein, TP53BPL, tumor suppressor p53-binding protein 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10210

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9NS56

Gene Symbols:
TOPORS

Immunogen:
Between 995 and 1045

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-1975

--


Antigen:
Abraxas

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABRAXAS1

Gene Alias:
UNQ496/PRO1013, ABRA1, CCDC98, FLJ11520, FLJ12642, FLJ13614, BRCA1-A complex subunit Abraxas, abraxas protein, coiled-coil domain containing 98, coiled-coil domain-containing protein 98

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84142

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.2 mg/ml

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q6UWZ7

Gene Symbols:
ABRAXAS1

Immunogen:
Between 350 and 400

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG