50-156-20
TNF alpha Monoclonal Antibody (TN3-19.12), PE-Cyanine7, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-20-Each-of-1 | In Stock | ₹ 31,913.88 |
50-156-20 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,913.88
GST (18%): ₹ 5,744.498
Total Price: ₹ 37,658.378
Antigen
TNF alpha
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P06804, P16599
Gene Symbols
Tnf
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21926, 24835
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
TN3-19.12
Conjugate
PE-Cyanine7
Gene
Tnf
Gene Alias
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Host Species
Armenian Hamster
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description: The TN3-19.12 monoclonal antibody reacts with mouse, rat, and rabbit tumor necrosis factor-alpha (TNF alpha), but not with human TNF alpha
- The TN3-19.12 antibody is a neutralizing antibody
- Mouse TNF alpha is a 17 kDa factor produced by macrophages, monocytes, neutrophils, CD4+ T cells and NK cells
- A 26 kDa form of TNF alpha is expressed as a membrane-bound molecule
- TNF alpha is cytolytic and plays an important role in immune regulation
- Dimers and trimers of TNF alpha have been observed
- Applications Reported: This TN3-19 antibody has been reported for use in intracellular staining followed by flow cytometric analysis, cytokine neutralization, and ELISA
- Applications Tested: This TN3-19 antibody is offered in 2 formats: - μg size: has been tested by intracellular staining and flow cytometric analysis of stimulated mouse splenocytes
- This can be used at less than or equal to 1 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- - test size: has been pre-titrated and tested by intracellular staining and flow cytometric analysis of stimulated mouse splenocytes
- This can be used at 5 μL (1 μg) per test
- TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
- This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
- TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
- TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
- Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
- Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
- TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
- This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
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Antigen: TNF alpha
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.: P06804, P16599
Gene Symbols: Tnf
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21926, 24835
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Applications: Flow Cytometry
Clone: TN3-19.12
Conjugate: PE-Cyanine7
Gene: Tnf
Gene Alias: APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Host Species: Armenian Hamster
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TNF alpha
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.:
P06804, P16599
Gene Symbols:
Tnf
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21926, 24835
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid
Applications:
Flow Cytometry
Clone:
TN3-19.12
Conjugate:
PE-Cyanine7
Gene:
Tnf
Gene Alias:
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
Host Species:
Armenian Hamster
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MASTL
Classification: Polyclonal
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q96GX5
Gene Symbols: MASTL
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84930
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: MASTL
Gene Alias: GREATWALL, GW, GWL, MAST-L, RP11-85G18.2, THC2, hGWL, greatwall protein kinase, microtubule-associated serine/threonine-protein kinase-like, serine/threonine-protein kinase greatwall
Host Species: Rabbit
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MASTL
Classification:
Polyclonal
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q96GX5
Gene Symbols:
MASTL
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84930
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
MASTL
Gene Alias:
GREATWALL, GW, GWL, MAST-L, RP11-85G18.2, THC2, hGWL, greatwall protein kinase, microtubule-associated serine/threonine-protein kinase-like, serine/threonine-protein kinase greatwall
Host Species:
Rabbit
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MINK1
Classification: Polyclonal
Concentration: 0.2 mg/ml
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q8N4C8, Q9JM52
Gene Symbols: Mink1
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 50488, 50932
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Clone: __
Conjugate: Unconjugated
Gene: MINK1
Gene Alias: FLJ18426, FLJ38123, FLJ94103, ISK, JLNS, JLNS2, LQT2/5, LQT5, MGC33114, MinK
Host Species: Rabbit
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MINK1
Classification:
Polyclonal
Concentration:
0.2 mg/ml
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q8N4C8, Q9JM52
Gene Symbols:
Mink1
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
50488, 50932
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
MINK1
Gene Alias:
FLJ18426, FLJ38123, FLJ94103, ISK, JLNS, JLNS2, LQT2/5, LQT5, MGC33114, MinK
Host Species:
Rabbit
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MINK1
Classification: Polyclonal
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q8N4C8, Q9JM52
Gene Symbols: Mink1
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 50488, 50932
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Clone: __
Conjugate: Unconjugated
Gene: MINK1
Gene Alias: FLJ18426, FLJ38123, FLJ94103, ISK, JLNS, JLNS2, LQT2/5, LQT5, MGC33114, MinK
Host Species: Rabbit
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MINK1
Classification:
Polyclonal
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q8N4C8, Q9JM52
Gene Symbols:
Mink1
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
50488, 50932
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Clone:
__
Conjugate:
Unconjugated
Gene:
MINK1
Gene Alias:
FLJ18426, FLJ38123, FLJ94103, ISK, JLNS, JLNS2, LQT2/5, LQT5, MGC33114, MinK
Host Species:
Rabbit
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG