50-156-2497
NPM1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-2497-Each-of-1 | In Stock | ₹ 41,863.65 |
50-156-2497 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
NPM1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NPM1
Gene Alias
NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4869
Content And Storage
4° C
Form
Liquid
Applications
Immunoprecipitation
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
P06748
Gene Symbols
NPM1
Immunogen
Between 200 and 250
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
- NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
- NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
- In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
- Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
- While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
- Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
- Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.
Compare Similar Items
Show Difference
Antigen: NPM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4869
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: P06748
Gene Symbols: NPM1
Immunogen: Between 200 and 250
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NPM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4869
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P06748
Gene Symbols:
NPM1
Immunogen:
Between 200 and 250
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NPM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4869
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: P06748
Gene Symbols: NPM1
Immunogen: Between 200 and 250
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NPM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4869
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P06748
Gene Symbols:
NPM1
Immunogen:
Between 200 and 250
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NPM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18148, 4869
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Immunoprecipitation
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: P06748, Q61937
Gene Symbols: Npm1
Immunogen: Between 250 and 294
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NPM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 4869
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P06748, Q61937
Gene Symbols:
Npm1
Immunogen:
Between 250 and 294
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NPM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18148, 4869
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry, Immunoprecipitation
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: P06748, Q61937
Gene Symbols: NPM1
Immunogen: Between 250 and 294
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NPM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
NPM, Nucleolar phosphoprotein B23, Numatrin, Nucleolar protein NO38
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18148, 4869
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry, Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P06748, Q61937
Gene Symbols:
NPM1
Immunogen:
Between 250 and 294
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG