50-156-2788

BRCC36 Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-156-2788-Each-of-1 In Stock ₹ 11,905.67

50-156-2788 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

BRCC36

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

P46736, P46737

Gene Symbols

Brcc3

Immunogen

Between 266 and 316

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

BRCC3

Gene Alias

RP11-143H17.2, BRCC36, C6.1A, CXorf53; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36; lys-63-specific deubiquitinase BRCC36

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

210766, 79184

Content And Storage

4° C

Form

Liquid

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Based on 100% sequence identity, this antibody is predict Together with the breast and ovarian predisposition proteins BRCA1 and BRCA2 and RAD51 and BRCC45, BRCC36 forms a holoenzyme complex that possesses a ubiquitin E3 ligase activity
  • Aberrant levels of BRCC36 were detected in sporadic breast tumors and depletion of either BRCC36 or BRCC45 by siRNA resulted in increased sensitivity to ionizing radiation and defects in the G2/M checkpoint, indicating that BRCC36 acts to enhance cellular survival following DNA damage
  • Recent experiments have shown that BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation, suggesting that BRCC36 may be an important target in the treatment of radiation-resistant breast tumors
  • At least two isoforms of BRCC36 are known to exist.

Compare Similar Items

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Bethyl Laboratories, Inc

50-156-2788

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Antigen:
BRCC36

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P46736, P46737

Gene Symbols:
Brcc3

Immunogen:
Between 266 and 316

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
BRCC3

Gene Alias:
RP11-143H17.2, BRCC36, C6.1A, CXorf53; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36; lys-63-specific deubiquitinase BRCC36

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
210766, 79184

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-2790

--


Antigen:
SSA1

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P19474

Gene Symbols:
TRIM21

Immunogen:
Between 250 and 300

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Gene:
TRIM21

Gene Alias:
TRIM21; tripartite motif-containing 21; RNF81, RO52, SSA, SSA1; 52kD Ro/SSA autoantigen; 52kDa ribonucleoprotein autoantigen SS-A/Ro; Sicca syndrome antigen A; Sjogren syndrome antigen A1 (52kD, ribonucleoprotein autoantigen SS-A/Ro); Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); tripartite motif protein TRIM21; tripartite motif protein 21

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6737

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-2791

--


Antigen:
SSA1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P19474

Gene Symbols:
TRIM21

Immunogen:
Between 425 and 475

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
TRIM21

Gene Alias:
TRIM21; tripartite motif-containing 21; RNF81, RO52, SSA, SSA1; 52kD Ro/SSA autoantigen; 52kDa ribonucleoprotein autoantigen SS-A/Ro; Sicca syndrome antigen A; Sjogren syndrome antigen A1 (52kD, ribonucleoprotein autoantigen SS-A/Ro); Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); tripartite motif protein TRIM21; tripartite motif protein 21

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6737

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-2793

--


Antigen:
SSA1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P19474

Gene Symbols:
TRIM21

Immunogen:
Between 425 and 475

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
TRIM21

Gene Alias:
TRIM21; tripartite motif-containing 21; RNF81, RO52, SSA, SSA1; 52kD Ro/SSA autoantigen; 52kDa ribonucleoprotein autoantigen SS-A/Ro; Sicca syndrome antigen A; Sjogren syndrome antigen A1 (52kD, ribonucleoprotein autoantigen SS-A/Ro); Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); tripartite motif protein TRIM21; tripartite motif protein 21

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6737

Content And Storage:
4° C

Form:
Liquid