50-156-2832

RuvBL2 Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-2832-Each-of-1 In Stock ₹ 11,905.67

50-156-2832 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

RuvBL2

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

Q9WTM5, Q9Y230

Gene Symbols

RUVBL2

Immunogen

Between 1 and 50

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Gene

RUVBL2

Gene Alias

CGI-46, ECP51, RVB2, TIP48, TIP49B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10856, 20174

Content And Storage

4° C

Form

Liquid

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Based on 100% sequence identity, this antibody is predict Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5′ to 3′) activity
  • Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A
  • This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription
  • This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair
  • The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400
  • NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage
  • RUVBL2 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex
  • May also inhibit the transcriptional activity of ATF2.

Compare Similar Items

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Bethyl Laboratories, Inc

50-156-2832

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Antigen:
RuvBL2

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q9WTM5, Q9Y230

Gene Symbols:
RUVBL2

Immunogen:
Between 1 and 50

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
RUVBL2

Gene Alias:
CGI-46, ECP51, RVB2, TIP48, TIP49B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10856, 20174

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-2835

--


Antigen:
MCEF

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9UHB7

Gene Symbols:
AFF4

Immunogen:
Between 50 and 100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Gene:
AFF4

Gene Alias:
AF5Q31, MCEF, AF4/FMR2 family member 4, ALL1-fused gene from chromosome 5q31 protein, major CDK9 elongation factor-associated protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27125

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-2837

--


Antigen:
MCEF

Classification:
Polyclonal

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9UHB7

Gene Symbols:
AFF4

Immunogen:
Between 1113 and 1163

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation

Conjugate:
Unconjugated

Gene:
AFF4

Gene Alias:
AF5Q31, MCEF, AF4/FMR2 family member 4, ALL1-fused gene from chromosome 5q31 protein, major CDK9 elongation factor-associated protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27125

Content And Storage:
4° C

Form:
Liquid

Img

Bethyl Laboratories, Inc

50-156-2841

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Antigen:
RNF219

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q5W0B1

Gene Symbols:
RNF219

Immunogen:
Between 676 and 726

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
RNF219

Gene Alias:
C13orf7, chromosome 13 open reading frame 7, FLJ13449

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79596

Content And Storage:
4° C

Form:
Liquid