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50-156-3878

UCH-L3 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-156-3878-Each-of-1 In Stock ₹ 11,905.67

50-156-3878 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

UCH-L3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UCHL3

Gene Alias

ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin thioesterase L3; ubiquitin thiolesterase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7347

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

P15374

Gene Symbols

UCHL3

Immunogen

Between 1 and 50

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine and Pig The two ubiquitin C-terminal hydrolase (UCH) enzymes, UCHL1 and UCHL3, deubiquitinate ubiquitin-protein conjugates and control the cellular balance of ubiquitin
  • UCHL1 and UCHL3 are both small proteins of ∽220 amino acids that share more than 40% amino acid sequence identity
  • UCHL3 is universally expressed in all tissues, while UCHL1 is expressed exclusively in neuronal tissue, testis and ovary
  • The activity of UCHL3 is more than 200 fold higher than UCHL1 when a fluorogenic ubiquitin substrate is used
  • UCHL1 associates with monoubiquitin and UCHL3 binds to Nedd8, ubiquitin-like protein
  • UCHL1 and UCHL3 play a role in the regulation of neuronal development and spermatogenesis
  • UCHL1 is involved in the pathogenesis of Parkinson′s disease (PD) and Alzheimer′s disease (AD)
  • Down-regulation and extensive oxidative modification of UCHL1 have been observed in the brains of AD patients as well as PD patients.

Compare Similar Items

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Img

Bethyl Laboratories, Inc

50-156-3878

--

Antigen:
UCH-L3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UCHL3
Gene Alias:
ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin thioesterase L3; ubiquitin thiolesterase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7347
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P15374
Gene Symbols:
UCHL3
Immunogen:
Between 1 and 50
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-3882

--

Antigen:
WWP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WWP1
Gene Alias:
WW domain containing E3 ubiquitin protein ligase 1, hSDRP1, Tiul1, AIP5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11059
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9H0M0
Gene Symbols:
WWP1
Immunogen:
Between 200 and 250
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-3885

--

Antigen:
WWP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WWP1
Gene Alias:
WW domain containing E3 ubiquitin protein ligase 1, hSDRP1, Tiul1, AIP5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11059
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9H0M0
Gene Symbols:
WWP1
Immunogen:
Between 300 and 350
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-3888

--

Antigen:
Daple
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCDC88C
Gene Alias:
Coiled-coil domain-containing protein 88C, DAPLE, Dvl-associating protein with a high frequency of leucine residues, hDaple, HkRP2, hook-related protein 2, KIAA1509, SCA40, spinocerebellar ataxia 40
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
440193
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9P219
Gene Symbols:
CCDC88C
Immunogen:
Between 1450 and 1500
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG