50-156-5469

SHARPIN Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-5469-Each-of-1 In Stock ₹ 41,863.65

50-156-5469 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

SHARPIN

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SHARPIN

Gene Alias

SIPL1, SHANK-associated RH domain interactor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

81858

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

Q9H0F6

Gene Symbols

SHARPIN

Immunogen

Between 25 and 75

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Bovine Component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
  • LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways
  • Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation
  • LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex
  • Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-156-5469

--


Antigen:
SHARPIN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SHARPIN

Gene Alias:
SIPL1, SHANK-associated RH domain interactor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
81858

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9H0F6

Gene Symbols:
SHARPIN

Immunogen:
Between 25 and 75

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-5472

--


Antigen:
RNF31

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNF31

Gene Alias:
RNF31; ZIBRA; FLJ10111; FLJ23501; zinc in-between-ring-finger ubiquitin-associated domain; ring finger protein 31; MGC19975; zinc in-between-RING-finger ubiquitin-associated domain protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
268749, 55072

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q924T7, Q96EP0

Gene Symbols:
RNF31

Immunogen:
Between 1022 and 1072

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-5477

--


Antigen:
PARN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PARN

Gene Alias:
DAN, deadenylating nuclease; deadenylation nuclease; poly(A)-specific ribonuclease PARN; polyadenylate-specific ribonuclease

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5073

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O95453

Gene Symbols:
PARN

Immunogen:
Between 539 and 589

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-5480

--


Antigen:
PARN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PARN

Gene Alias:
DAN, deadenylating nuclease; deadenylation nuclease; poly(A)-specific ribonuclease PARN; polyadenylate-specific ribonuclease

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5073, 74108

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O95453, Q8VDG3

Gene Symbols:
PARN

Immunogen:
Between 589 and 639

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG