50-156-5943

Beta-Arrestin 1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-5943-Each-of-1 In Stock ₹ 41,863.65

50-156-5943 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

Beta-Arrestin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARRB1

Gene Alias

BARRES

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

408

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

P49407

Gene Symbols

ARRB1

Immunogen

Between 368 and 418

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system
  • Serving as an adaptor or scaffold maolecule, beta Arrestin 1 is essential for mitogenic signalling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor)
  • After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosporylated by G-protein receptor kinases (GRKs) on serine residues
  • Beta Arrestin 1 in the cytosol is phosphorylated by ERK1&2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane
  • Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1&2 signaling pathway.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-156-5943

--


Antigen:
Beta-Arrestin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARRB1

Gene Alias:
BARRES

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
408

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P49407

Gene Symbols:
ARRB1

Immunogen:
Between 368 and 418

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-5950

--


Antigen:
SNM1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCLRE1A

Gene Alias:
PSO2, SNM1, SNM1A, DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae), DNA cross-link repair 1A protein, DNA-crosslink repair gene SNM1, PSO2 homolog, SNM1 homolog A, hSNM1A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9937

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q6PJP8

Gene Symbols:
DCLRE1A

Immunogen:
Between 425 and 475

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-5952

--


Antigen:
NDRG3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NDRG3

Gene Alias:
N-myc downstream-regulated gene 3 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57446

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9UGV2

Gene Symbols:
NDRG3

Immunogen:
Between 300 and 350

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-5956

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Antigen:
ZO-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TJP2

Gene Alias:
Friedreich ataxia region gene X104 (tight junction protein ZO-2); tight junction protein ZO 2; tight junction protein ZO-2; zona occludens protein 2; zonula occludens protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9414

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q9UDY2

Gene Symbols:
TJP2

Immunogen:
Between 150 and 200

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG