50-156-6182

Lasu1/Ureb1 Goat anti-Human, Polyclonal, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

Select a Size

Pack Size SKU Availability Price
Each of 1 50-156-6182-Each-of-1 In Stock ₹ 41,863.65

50-156-6182 - Each of 1

₹ 41,863.65

In Stock

Quantity

1

Base Price: ₹ 41,863.65

GST (18%): ₹ 7,535.457

Total Price: ₹ 49,399.107

Antigen

Lasu1/Ureb1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HUWE1

Gene Alias

RP3-339A18.4, ARF-BP1, HECTH9, HSPC272, Ib772, LASU1, MULE, UREB1; ARF binding protein 1; ARF-binding protein 1; BJ-HCC-24 tumor antigen; E3 ubiquitin-protein ligase HUWE1; HECT domain protein LASU1; HECT, UBA and WWE domain-containing protein 1; Mcl-1 ubiquitin ligase E3; URE-B1; URE-binding protein 1; homologous to E6AP carboxyl terminus homologous protein 9; large structure of UREB1; upstream regulatory element-binding protein 1

Host Species

Goat

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10075

Content And Storage

4° C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/ml

Formulation

phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.

Q7Z6Z7

Gene Symbols

HUWE1

Immunogen

Between 2250 and 2300

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • The ARF tumor suppressor is a critical regulator of p53 stability
  • In addition to p53, ARF1 binds to other proteins such as MDM2 and ARF-BP1, a large protein containing HECT, UBA and WWE motifs
  • ARF-BP1 directly binds and ubiquitinates p53; this activity is inhibited by ARF, indicating that ARF-BP1 is a critical mediator of the p53-dependent and p53-independent tumor suppressor functions of ARF
  • ARF-BP1 can also catalyze the polyubiquitination of Mcl-1, an anti-apoptotic Bcl-2 family member involved in DNA damage-induced apoptosis
  • Elimination of ARF-BP1 expression by RNA interference stabilized Mcl-1 protein, resulting in an attenuation of apoptosis induced by DNA-damage agents.

Compare Similar Items

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Img

Bethyl Laboratories, Inc

50-156-6182

--


Antigen:
Lasu1/Ureb1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HUWE1

Gene Alias:
RP3-339A18.4, ARF-BP1, HECTH9, HSPC272, Ib772, LASU1, MULE, UREB1; ARF binding protein 1; ARF-binding protein 1; BJ-HCC-24 tumor antigen; E3 ubiquitin-protein ligase HUWE1; HECT domain protein LASU1; HECT, UBA and WWE domain-containing protein 1; Mcl-1 ubiquitin ligase E3; URE-B1; URE-binding protein 1; homologous to E6AP carboxyl terminus homologous protein 9; large structure of UREB1; upstream regulatory element-binding protein 1

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10075

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q7Z6Z7

Gene Symbols:
HUWE1

Immunogen:
Between 2250 and 2300

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-6183

--


Antigen:
Lasu1/Ureb1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HUWE1

Gene Alias:
RP3-339A18.4, ARF-BP1, HECTH9, HSPC272, Ib772, LASU1, MULE, UREB1; ARF binding protein 1; ARF-binding protein 1; BJ-HCC-24 tumor antigen; E3 ubiquitin-protein ligase HUWE1; HECT domain protein LASU1; HECT, UBA and WWE domain-containing protein 1; Mcl-1 ubiquitin ligase E3; URE-B1; URE-binding protein 1; homologous to E6AP carboxyl terminus homologous protein 9; large structure of UREB1; upstream regulatory element-binding protein 1

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10075

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
Q7Z6Z7

Gene Symbols:
HUWE1

Immunogen:
Between 2250 and 2300

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-6184

--


Antigen:
H2AX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AFX

Gene Alias:
H2A/X, H2AX, H2AX histone, histone H2AX

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15270, 3014

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/ml

Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8

Gene Accession No.:
P16104, P27661

Gene Symbols:
H2AFX

Immunogen:
C-terminus

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Bethyl Laboratories, Inc

50-156-6186

--


Antigen:
H2AX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AFX

Gene Alias:
H2A/X, H2AX, H2AX histone, histone H2AX

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15270, 3014

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
__

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
P16104, P27661

Gene Symbols:
H2AFX

Immunogen:
C-terminus

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG