KIF5B Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Description

• The recommended shelf life for this product is 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat Kinesin belongs to the group of microtubule-associatied motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy
• Conventional kinesin, member of kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells
• Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa
• Each heavy chain contains an N-terminal globular motordomain with both a microtuble-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding
• Light chains may have a regulatory function.