50-156-8414
SMCR8 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-8414-Each-of-1 | In Stock | ₹ 41,863.65 |
50-156-8414 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
SMCR8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMCR8
Gene Alias
FLJ34716
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
140775, 237782
Content And Storage
4° C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q3UMB5, Q8TEV9
Gene Symbols
Smcr8
Immunogen
Between 600 and 650
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy
- In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation
- The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity
- Acts as a regulator of mTORC1 signaling by promoting phosphorylation of mTORC1 substrates
- In addition to its activity in the cytoplasm within the C9orf72-SMCR8 complex, SMCR8 also localizes in the nucleus, where it associates with chromatin and negatively regulates expression of suppresses ULK1 and WIPI2 genes.
Compare Similar Items
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Antigen: SMCR8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMCR8
Gene Alias: FLJ34716
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 140775, 237782
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q3UMB5, Q8TEV9
Gene Symbols: Smcr8
Immunogen: Between 600 and 650
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SMCR8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMCR8
Gene Alias:
FLJ34716
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
140775, 237782
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q3UMB5, Q8TEV9
Gene Symbols:
Smcr8
Immunogen:
Between 600 and 650
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ZCRB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZCRB1
Gene Alias: MADP-1, MADP1, RBM36, ZCCHC19; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12 snRNP 31K; U11/U12-31K; zinc finger CCHC-type and RNA-binding motif-containing protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 67197, 85437
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q8TBF4, Q9CZ96
Gene Symbols: ZCRB1
Immunogen: Between 155 and 205
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ZCRB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZCRB1
Gene Alias:
MADP-1, MADP1, RBM36, ZCCHC19; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12 snRNP 31K; U11/U12-31K; zinc finger CCHC-type and RNA-binding motif-containing protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
67197, 85437
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q8TBF4, Q9CZ96
Gene Symbols:
ZCRB1
Immunogen:
Between 155 and 205
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: C9orf40
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C9orf40
Gene Alias: FLJ10110
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 225995, 55071
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q8IXQ3, Q8VCE4
Gene Symbols: C9orf40, D030056L22Rik
Immunogen: Between 75 and 125
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
C9orf40
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C9orf40
Gene Alias:
FLJ10110
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
225995, 55071
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q8IXQ3, Q8VCE4
Gene Symbols:
C9orf40, D030056L22Rik
Immunogen:
Between 75 and 125
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: C9orf40
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C9orf40
Gene Alias: FLJ10110
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 225995, 55071
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.: Q8IXQ3, Q8VCE4
Gene Symbols: C9orf40, D030056L22Rik
Immunogen: Between 75 and 125
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
C9orf40
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C9orf40
Gene Alias:
FLJ10110
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
225995, 55071
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Accession No.:
Q8IXQ3, Q8VCE4
Gene Symbols:
C9orf40, D030056L22Rik
Immunogen:
Between 75 and 125
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG