50-156-9852
PTRH2/BIT1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Manufacturer: Bethyl Laboratories, Inc
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-156-9852-Each-of-1 | In Stock | ₹ 41,863.65 |
50-156-9852 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,863.65
GST (18%): ₹ 7,535.457
Total Price: ₹ 49,399.107
Antigen
PTRH2/BIT1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTRH2
Gene Alias
OTTHUMP00000205936; PTH 2; bcl-2 inhibitor of transcription 1; peptidyl-tRNA hydrolase 2, mitochondrial
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51651
Content And Storage
4° C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/ml
Formulation
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.
Q9Y3E5
Gene Symbols
PTRH2
Immunogen
Between 129 and 179
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading
- Anoikis is the molecular mechanism of apoptosis induced by integrin detachment
- Bit1 (Bcl-2 inhibitor of transcription 1) was recently identified as being involved in this process
- Bit1 is a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis where it forms a complex with AES, a small Groucho/transducin-like enhancer of split (TLE) protein and induces caspase-independent apoptosis
- Both AES and TLE proteins are transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination
- It has been suggested that Bit1-AES complexes turn off a survival-promoting gene transcription program controlled by TLE
- Interestingly, apoptosis of cells transfected with Bit1 and AES could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.
Compare Similar Items
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Antigen: PTRH2/BIT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTRH2
Gene Alias: OTTHUMP00000205936; PTH 2; bcl-2 inhibitor of transcription 1; peptidyl-tRNA hydrolase 2, mitochondrial
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51651
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q9Y3E5
Gene Symbols: PTRH2
Immunogen: Between 129 and 179
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PTRH2/BIT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTRH2
Gene Alias:
OTTHUMP00000205936; PTH 2; bcl-2 inhibitor of transcription 1; peptidyl-tRNA hydrolase 2, mitochondrial
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51651
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q9Y3E5
Gene Symbols:
PTRH2
Immunogen:
Between 129 and 179
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TBC1D1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBC1D1
Gene Alias: TBC, TBC1; TBC1 domain family member 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23216
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q86TI0
Gene Symbols: TBC1D1
Immunogen: Between 1118 and 1168
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TBC1D1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBC1D1
Gene Alias:
TBC, TBC1; TBC1 domain family member 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23216
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q86TI0
Gene Symbols:
TBC1D1
Immunogen:
Between 1118 and 1168
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TBC1D1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBC1D1
Gene Alias: TBC, TBC1; TBC1 domain family member 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23216
Content And Storage: 4° C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: Q86TI0
Gene Symbols: TBC1D1
Immunogen: Between 1118 and 1168
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TBC1D1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBC1D1
Gene Alias:
TBC, TBC1; TBC1 domain family member 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23216
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
Q86TI0
Gene Symbols:
TBC1D1
Immunogen:
Between 1118 and 1168
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TMED10/TMP21
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMED10
Gene Alias: Transmembrane emp24 domain-containing protein 10 , Transmembrane protein Tmp21 , 21 kDa transmembrane trafficking prote
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10972, 68581
Content And Storage: 4° C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/ml
Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.: P49755, Q9D1D4
Gene Symbols: TMED10
Immunogen: Between 50 and 100
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TMED10/TMP21
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMED10
Gene Alias:
Transmembrane emp24 domain-containing protein 10 , Transmembrane protein Tmp21 , 21 kDa transmembrane trafficking prote
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10972, 68581
Content And Storage:
4° C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/ml
Formulation:
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene Accession No.:
P49755, Q9D1D4
Gene Symbols:
TMED10
Immunogen:
Between 50 and 100
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG