50-157-1254

HLA-DR Mouse anti-Human, Clone: LN3, Bethyl Laboratories

Manufacturer: Bethyl Laboratories, Inc

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Pack Size SKU Availability Price
Each of 1 50-157-1254-Each-of-1 In Stock ₹ 12,496.04

50-157-1254 - Each of 1

₹ 12,496.04

In Stock

Quantity

1

Base Price: ₹ 12,496.04

GST (18%): ₹ 2,249.287

Total Price: ₹ 14,745.327

Antigen

HLA-DR

Classification

Monoclonal

Conjugate

Unconjugated

Gene

HLA-DRA

Gene Alias

CD74 antigen, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia-associated invariant chain, MHC HLA-DR gamma chain, gamma chain of class II antigens, ia antigen-associated invariant chain, HLADG, DHLAG, IA-gamma

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3122

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

LN3

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P01903

Gene Symbols

HLA-DRA

Immunogen

Activated human peripheral blood mononuclear cells

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections
  • For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
  • HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB)
  • The alpha chain gene contains 5 exons
  • Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail
  • DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5
  • Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
  • Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • HLA-DR is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes
  • Three loci, DR, DQ and DP, encode the major expressed products of the human class II region
  • The human MHC class II molecules bind intracellularly processed peptides, present them to T-helper cells, and have a critical role in the initiation of the immune response.

Compare Similar Items

Show Difference

Img

Bethyl Laboratories, Inc

50-157-1254

--


Antigen:
HLA-DR

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
HLA-DRA

Gene Alias:
CD74 antigen, HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia-associated invariant chain, MHC HLA-DR gamma chain, gamma chain of class II antigens, ia antigen-associated invariant chain, HLADG, DHLAG, IA-gamma

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3122

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
LN3

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P01903

Gene Symbols:
HLA-DRA

Immunogen:
Activated human peripheral blood mononuclear cells

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Img

Fischer Scientific

50-157-1255

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Antigen:
HdmX/MDM4

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene:
MDM4

Gene Alias:
RP11-430C7.1, DKFZp781B1423, HDMX, MDMX, MGC132766, MRP1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4194

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Clone:
BL-3-2F2

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
O15151

Gene Symbols:
MDM4

Immunogen:
Between 125 and 175

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-157-1256

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Antigen:
HdmX/MDM4

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene:
MDM4

Gene Alias:
RP11-430C7.1, DKFZp781B1423, HDMX, MDMX, MGC132766, MRP1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4194

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Clone:
BL-3-2F2

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
O15151

Gene Symbols:
MDM4

Immunogen:
Between 125 and 175

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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50-157-1257

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Antigen:
HIF1-alpha

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene:
HIF1A

Gene Alias:
Hypoxia inducing factor 1

Host Species:
Rabbit

Purification Method:
Ion-exchange chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3091

Content And Storage:
4° C

Form:
Liquid

Applications:
ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
BL-124-3F7

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
Q16665

Gene Symbols:
HIF1A

Immunogen:
Between 433 and 826

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG