50-157-1280

Phospho-KAP-1 (Ser824) Recombinant Rabbit Monoclonal Antibody (BL-246-7B5), Bethyl Laboratories

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-157-1280-Each-of-1 In Stock ₹ 12,496.04

50-157-1280 - Each of 1

₹ 12,496.04

In Stock

Quantity

1

Base Price: ₹ 12,496.04

GST (18%): ₹ 2,249.287

Total Price: ₹ 14,745.327

Antigen

Phospho-KAP-1 (Ser824)

Classification

Recombinant Monoclonal

Conjugate

Unconjugated

Gene

TRIM28

Gene Alias

Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p

Host Species

Rabbit

Purification Method

Purified

Regulatory Status

RUO

Gene ID (Entrez)

10155

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

BL-246-7B5

Formulation

BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.

Q13263

Gene Symbols

TRIM28

Immunogen

Surrounding serine 824

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Application Note: For ICC, formaldehyde fixation is recommended
  • Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells
  • For IHC, epitope retrieval with c The KRAB (Kruppel-associated box) domain is about 45 amino acids in length and is a transcriptional repression domain found in numerous transcription factors
  • There have been identified over 220 KRAB-zinc finger protein (KRAB-ZFP) genes in the human genome
  • These proteins functionally repress transcription via specific interactions with KAP-1 (KRAB-associated protein 1)
  • KAP-1 is an 835 amino acid polypeptide that contains a RING finger, B boxes, and a PHD finger
  • KAP-1 has been shown to form complexes with KRAB-domain transcription factors and increase the efficiency with which they mediate repression
  • KAP-1 has also been shown to directly interact with HP1 (heterochromatin protein 1) and KRAZ1 (Kruppel-associated box-containing zinc finger protein 1)
  • KAP-1 directly targets KRAZ1 to the foci of centromeric heterochromatin containing HP1alpha, thus helping to regulate transcriptional repression
  • Studies have shown that KAP-1 mutants with the ability to bind KRAB but unable to bind HP1 leads to random distribution of KRAZ1 and strong transcriptional activation.

Compare Similar Items

Show Difference

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Fischer Scientific

50-157-1280

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Antigen:
Phospho-KAP-1 (Ser824)

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene:
TRIM28

Gene Alias:
Transcription intermediary factor 1-beta, Tripartite motif protein 28, Nuclear corepressor KAP-1, KRAB-associated protein 1, KAP-1, KRAB-interacting p

Host Species:
Rabbit

Purification Method:
Purified

Regulatory Status:
RUO

Gene ID (Entrez):
10155

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
BL-246-7B5

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
Q13263

Gene Symbols:
TRIM28

Immunogen:
Surrounding serine 824

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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50-157-1285

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Antigen:
CD3E

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene:
CD3E

Gene Alias:
FLJ18683; T3E; TCRE; CD3-epsilon; CD3e antigen; epsilon polypeptide TiT3 complex; T-cell antigen receptor complex; epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; HCD3

Host Species:
Rabbit

Purification Method:
Purified

Regulatory Status:
RUO

Gene ID (Entrez):
916

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
BL-298-5D12

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
P07766

Gene Symbols:
CD3E

Immunogen:
Between 157 and 207

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

50-157-1286

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Antigen:
CD3E

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene:
CD3E

Gene Alias:
FLJ18683; T3E; TCRE; CD3-epsilon; CD3e antigen; epsilon polypeptide TiT3 complex; T-cell antigen receptor complex; epsilon subunit of T3; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; HCD3

Host Species:
Rabbit

Purification Method:
Purified

Regulatory Status:
RUO

Gene ID (Entrez):
916

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
BL-298-5D12

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
P07766

Gene Symbols:
CD3E

Immunogen:
Between 157 and 207

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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50-157-1287

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Antigen:
CD247/CD3Z

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene:
CD247

Gene Alias:
T3Z, CD3H, CD3Q, TCRZ, CD3-ZETA

Host Species:
Rabbit

Purification Method:
Purified

Regulatory Status:
RUO

Gene ID (Entrez):
919

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
BL-336-1B2

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
P20963

Gene Symbols:
CD247

Immunogen:
Between 114 and 164

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG