Ubiquitin Polyclonal Antibody, Bethyl Laboratories

Description

• The recommended shelf life for this product is 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, D
• melanogaster, Zebrafish, X
• laevis, X
• tropicalis, Chicken, Sheep, Bovine, Dog, Horse, Ra Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein
• This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus
• When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a
• Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins
• It contains C4-type zinc finger domains and is located in the cytoplasm
• Pseudogenes derived from this gene are present in the genome
• As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi.