50-157-2194

BubR1 Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-157-2194-Each-of-1 In Stock ₹ 11,905.67

50-157-2194 - Each of 1

₹ 11,905.67

In Stock

Quantity

1

Base Price: ₹ 11,905.67

GST (18%): ₹ 2,143.021

Total Price: ₹ 14,048.691

Antigen

BubR1

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

O60566

Gene Symbols

BUB1B

Immunogen

Between 1 and 50

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry

Conjugate

Unconjugated

Gene

BUB1B

Gene Alias

BUB1B, Budding Uninhibited by Benzimidazoles 1 beta, hBUBR1, MAD3L

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

701

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee and Crab-eating macaque Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to maligt transformations
  • Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
  • They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
  • hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
  • BUBR1 has been detected in human cancers
  • It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-157-2194

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Antigen:
BubR1

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O60566

Gene Symbols:
BUB1B

Immunogen:
Between 1 and 50

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
BUB1B

Gene Alias:
BUB1B, Budding Uninhibited by Benzimidazoles 1 beta, hBUBR1, MAD3L

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
701

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

50-157-2197

--


Antigen:
CASC5

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q8NG31

Gene Symbols:
KNL1

Immunogen:
Between 300 and 350

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
KNL1

Gene Alias:
Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57082

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

50-157-2198

--


Antigen:
CASC5

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q8NG31

Gene Symbols:
KNL1

Immunogen:
Between 300 and 350

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
KNL1

Gene Alias:
Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57082

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

50-157-2199

--


Antigen:
MCAK

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q99661

Gene Symbols:
KIF2C

Immunogen:
Between 50 and 100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
KIF2C

Gene Alias:
RP11-269F19.1, KNSL6, MCAK, kinesin-like 6; kinesin-like protein 6; kinesin-like protein KIF2C; mitotic centromere-associated kinesin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11004

Content And Storage:
4° C

Form:
Liquid