50-157-2343

PDZ-RhoGEF Polyclonal Antibody, Bethyl Laboratories

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 50-157-2343-Each-of-1 In Stock ₹ 44,377.41

50-157-2343 - Each of 1

₹ 44,377.41

In Stock

Quantity

1

Base Price: ₹ 44,377.41

GST (18%): ₹ 7,987.934

Total Price: ₹ 52,365.344

Antigen

PDZ-RhoGEF

Classification

Polyclonal

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.

O15085

Gene Symbols

ARHGEF11

Immunogen

Between 1472 and 1522

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry

Conjugate

Unconjugated

Gene

ARHGEF11

Gene Alias

RP11-356J7.2, GTRAP48, PDZ-RHOGEF, Rho guanine exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator, glutamate transporter EAAT4-associated protein 48, rho guanine nucleotide exchange factor 11

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9826

Content And Storage

4° C

Form

Liquid

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Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee ARHGEF11 is a 1527 amino acid protein with tandem dbl homology and pleckstrin homology domains, PDZ domain, two proline rich sequences and a regulatory G protein-signaling (RGS) sequence
  • It acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase, but not for RAC1 or CDC42 and acts as GTPase-activating protein (GAP) for GNA12 and GNA13
  • It forms a complex with G proteins and stimulates neurite through retraction Rho-dependent signals
  • ARHGEF11 increases glutamate transport 4-fold
  • It interacts with EAAT4 and modulates its uptake activity and perisynaptic distribution at glutamatergic synapses
  • It is known to induce the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia
  • It is ubiquitously expressed, in brain, lung, liver, kidney and skeletal muscle.

Compare Similar Items

Show Difference

Img

Fischer Scientific

50-157-2343

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Antigen:
PDZ-RhoGEF

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O15085

Gene Symbols:
ARHGEF11

Immunogen:
Between 1472 and 1522

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
ARHGEF11

Gene Alias:
RP11-356J7.2, GTRAP48, PDZ-RHOGEF, Rho guanine exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator, glutamate transporter EAAT4-associated protein 48, rho guanine nucleotide exchange factor 11

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9826

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

50-157-2344

--


Antigen:
PDZ-RhoGEF

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
O15085

Gene Symbols:
ARHGEF11

Immunogen:
Between 1472 and 1522

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
ARHGEF11

Gene Alias:
RP11-356J7.2, GTRAP48, PDZ-RHOGEF, Rho guanine exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator, glutamate transporter EAAT4-associated protein 48, rho guanine nucleotide exchange factor 11

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9826

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

50-157-2347

--


Antigen:
KSRP

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q3U0V1, Q92945

Gene Symbols:
Khsrp

Immunogen:
Between 100 and 150

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
KHSRP

Gene Alias:
KHE3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16549, 8570

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

50-157-2348

--


Antigen:
KSRP

Classification:
Polyclonal

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Accession No.:
Q3U0V1, Q92945

Gene Symbols:
KHSRP

Immunogen:
Between 100 and 150

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Gene:
KHSRP

Gene Alias:
KHE3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16549, 8570

Content And Storage:
4° C

Form:
Liquid