BRAF Polyclonal Antibody, Bethyl Laboratories

Description

• The recommended shelf life for this product is 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Small-eared galago a B-raf belongs to the raf/mil family of serine/threonine protein kinases
• This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion
• Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance
• Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, maligt melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung
• A pseudogene, which is located on chromosome X, has been identified for this gene.